rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Regulators and effectors of small GTPases
    sub title: Rho family
  name:
    name part: Balch, William Edward
    name part: 1949-
  name:
    name part: Der, Channing J.
  name:
    name part: Hall, A. (Alan)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: ne
    place:
      place term: Amsterdam
    place:
      place term: Boston
    publisher: Elsevier
    publisher: Academic Press
    date issued: Ã2006
    date issued: 2006
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xliii, 798 pages) : illustrations.
  abstract: The Ras superfamily (>150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl and dynamin involved in vesicle budding/fission. These GTPases act as molecular switches and their activities are controlled by a large number of regulatory molecules that affect either GTP loading (guanine nucleotide exchange factors or GEFs) or GTP hydrolysis (GTPase activating proteins or GAPs). In their active state, they interact with a continua.
  table of contents: Purification and Biochemical Properties of Rac1, 2, 3 and the Splice Variant Rac1b -- Biochemical Analyses of the Wrch Atypical Rho Family GTPases -- Purification of P-Rex1 from Neutrophils and Nucleotide Exchange Assay -- In Vitro Guanine Nucleotide Exchange Activity of DHR-2/DOCKER/CZH2 Domains -- Biochemical Characterization of the Cool (Cloned-Out-of-Library)/Pix (Pak-Interactive Exchange Factor) Proteins -- GEF and Glucosylation Assays on Liposome-Bound Rac -- Phosphorylation of RhoGDI by p21-activated kinase 1 -- Purification of ARAP3 and Characterization of GAP Activities -- Regulation of RhoGAP specificity by Phospholipids and Prenylation -- Purification and Activity of the Rho ADP-ribosylating binary C2/C3 Toxin -- Purification of TAT-C3 Exoenzyme -- Imaging and photobleach correction of Mero-CBD, Sensor of Endogenous Cdc42 Activation -- Cdc42 and PI(4,5)P2-induced actin Assembly in Xenopus Egg Extracts -- In vitro reconstitution of Cdc42-mediated actin assembly using purified components -- Biochemical analysis of mammalian formin effects on actin Dynamics -- Formin proteins: purification and measurement of effects on actin assembly -- Purification and kinase assay of PKN -- Purification and enzyme activity of ACK1 -- Direct Activation of purified phospholipase C epsilon by RhoA studied in reconstituted phospholipid Vesicles -- Regulation of PLCbeta isoforms by Rac -- Biochemical properties and Inhibitors of (N- )WASP -- The Use of GFP to localize Rho GTPases in living cells -- Analysis of the spatiotemporal activation of Rho GTPases using Raichu probes -- Measurement of activity of Rho GTPases during mitosis -- Inhibition of Rho GTPases by RNA interference -- RNA interference techniques to study epithelial cell adhesion and polarity -- Nucleofection of Primary Neurons -- Dock180-ELMO cooperation in Rac activation -- Rho GTPase activation by cell-cell adhesion -- Activation of Rap1, Cdc42, and Rac by nectin adhesion system -- Analysis of activated GAPs and …
  note: edited by William E. Balch, Channing J. Der, Alan Hall.
  note: Includes bibliographical references and indexes.
  subject:
    topic: Guanosine triphosphatase
  subject:
    topic: Rho GTPases
  subject:
    topic: SCIENCE
    topic: Life Sciences
    topic: Molecular Biology
  subject:
    topic: Guanosine triphosphatase
  subject:
    topic: Rho GTPases
  subject:
    topic: GTPasen
  subject:
    topic: Regelmechanismen
  subject:
    topic: Rab-Proteine
  subject:
    topic: Rho-Proteine
  subject:
    topic: rho GTP-Binding Proteins
    topic: physiology
  classification: QP601 .C57 v. 406
  classification: 572.8
  classification: W1 ME9615K v.406 2006
  classification: QU 55 R3449 2006
  classification: 35.74
  classification: 35.70
  related item:
    title info:
      title: Methods in enzymology ; v. 406
  identifier: 0080479391
  identifier: 9780080479392
  identifier: 0121828115
  identifier: 9780121828110
  identifier: https://www.sciencedirect.com/science/bookseries/00766879/406
  record info:
    record content source: MERUC
    record creation date: 060210
    record change date: 20180501121923.0
    record identifier: ocn441804750
    language of cataloging:
      language term: eng