http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Pharmacology of purine and pyrimidine receptors
1 online resource (xvi, 541 pages) : illustrations.
This is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors. Authors are the leading authorities in their fields Subject matter is important for understanding tissue protection Subject matter is of intense interest for new drug development.
Structure of the adenosine receptors: implications for drug discovery -- Adenosine receptors in health and disease -- Adenosine and the regulation of metabolism and body temperature -- Regulation of leukocyte function by adenosine receptors -- Role of adenosine A₂[B] receptors in inflammation -- Interplay of hypoxia and A₂[B] adenosine receptors in tissue protection -- Allosteric modulation of purine and pyrimidine receptors -- Molecular mechanisms of purine and pyrimidine nucleotide release -- Impact of ectoenzymes on P2 and P1 receptor signaling -- Ectonucleotidases as regulators of purinergic signaling in thrombosis, inflammation, and immunity -- P2X receptors in health and disease -- Molecular pharmacology, physiology, and structures of the P2Y receptors -- P2Y receptors in health and disease -- P2 receptor signaling in neurons and glial cells of the central nervous system -- Role of purinergic receptors in CNS function and neuroprotection.
edited by Kenneth A. Jacobson, Joel Linden.
Includes bibliographical references and index.
San Diego : Elsevier Academic Press, 2011
Advances in pharmacology (San Diego, Calif.) ; 61