rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Clinical trial design
    sub title: Bayesian and frequentist adaptive methods
  name:
    name part: Yin, Guosheng
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: Wiley InterScience (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: nju
    date issued: 2012
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xvii, 336 pages) : illustrations.
  abstract: There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. nevertheless, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. This book provides an overview of the fundamentals of clinical trials, the key terminologies and concepts, and a brief review and comparison on Bayesian and frequentist estimation and inference procedures. From the practical point of view, this book introduces various statistical methods that are commonly.
  table of contents: Front Matter -- Introduction -- Fundamentals of Clinical Trials -- Frequentist versus Bayesian Statistics -- Phase I Trial Design -- Phase II Trial Design -- Phase III Trial Design -- Adaptive Randomization -- Late-Onset Toxicity -- Drug-Combination Trials -- Targeted Therapy Design -- References -- Author Index -- Subject Index -- Wiley Series in Probability and Statistics.
  table of contents: Fundamentals of clinical trials -- Frequentist versus Bayesian statistics -- Phase I trial design -- Phase II trial design -- Phase III trial design -- Adaptive randomization -- Late onset toxicity -- Drug combination trials -- Targeted therapy design.
  note: Guosheng Yin.
  note: Includes bibliographical references and indexes.
  subject:
    topic: Clinical trials
    topic: Statistical methods
  subject:
    topic: Bayesian statistical decision theory
  subject:
    topic: Mathematical statistics
  subject:
    topic: Clinical Trials as Topic
    topic: methods
  subject:
    topic: Bayes Theorem
  subject:
    topic: Statistics as Topic
    topic: methods
  subject:
    topic: Bayes Theorem
  subject:
    topic: Clinical Trials as Topic
    topic: methods
  subject:
    topic: Clinical trials
  subject:
    topic: Statistics as Topic
    topic: methods
  subject:
    topic: Medicine
  subject:
    topic: MEDICAL
    topic: Laboratory Medicine
  subject:
    topic: Bayesian statistical decision theory
  subject:
    topic: Clinical trials
    topic: Statistical methods
  subject:
    topic: Mathematical statistics
  classification: R853.C55 Y56 2012
  classification: 615.50724
  classification: QV 771
  related item:
    title info:
      title: Clinical trial design
    name:
      name part: Yin, Guosheng.
    origin info:
      publisher: Hoboken, N.J. : John Wiley & Sons, ©2012
    identifier: (DLC) 2011033589
    identifier: (OCoLC)746461914
  related item:
    title info:
      title: Wiley series in probability and statistics
  identifier: 9781118183335
  identifier: 1118183339
  identifier: 9781118183304
  identifier: 1118183304
  identifier: 9780470581711
  identifier: 2011033589
  identifier: 10.1002/9781118183335 Wiley InterScience
  identifier: https://doi.org/10.1002/9781118183335
  record info:
    record content source: DG1
    record creation date: 120207
    record change date: 20170124071633.5
    record identifier: ocn775437755
    language of cataloging:
      language term: eng