rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Eukaryotic RNases and their partners in RNA degradation and biogenesis
    part number: Part B
  name:
    name part: Chanfreau, Guillaume.
  name:
    name part: Tamanoi, Fuyuhiko.
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: cau
    place:
      place term: San Diego
    publisher: Academic Press
    date issued: 2012
    edition: 1st ed.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource.
  abstract: This special volume of The Enzymes is targeted towards researchers in biochemistry, molecular and cell biology, pharmacology, and cancer. This thematic volume discusses Eukaryotic RNases and their partners in RNA degradation and biogenesis. Key features: * Contributions from leading authorities * Informs and updates on all the latest developments in the field.
  table of contents: Machine generated contents note: 1. Dicer Proteins and Their Role in Gene Silencing Pathways / Witold Filipowicz -- 1. Introduction -- 2. Dicers: RNase Ill Family Members with a Role in Gene Silencing -- 3. Mechanism of Processing and the Role of the Catalytic RNase Ill Domains -- 4. Role of Other Domains in Dicer Function -- 5. Domain Arrangement in Metazoan Dicers -- 6. Inside-Out Processing Mechanism by the Yeast Dicer -- 7. Function of Dicer in the Nucleus -- 8. Proteins Interacting with Dicer and the Assembly of RISC Effector Complexes -- 9. Future Perspectives -- Acknowledgments -- References -- 2. Loquacious, a Dicer Partner Protein, Functions in Both the MicroRNA and siRNA Pathways / Phillip D. Zamore -- 1. Introduction -- 2.miRNA and siRNA Pathways in the Fruit Fly Drosophila Melanogaster -- 3. Drosophila Dicer-1 and Dicer-2: Similar but Distinct Domain Structures -- 4. Conserved Partnerships Between Dicer and Dicer-Binding Partner dsRBD Proteins -- 5. Loqs Encodes Four Alternatively Spliced Isoforms -- 6. Loqs-PA and Loqs-PB Bind to Dicer-1, While Loqs-PD and R2D2 Bind to Dicer-2 -- 7. Partner Protein Mutant Phenotypes in Flies and Mammals -- 8. Loqs-PA and Loqs-PB Function in the miRNA Pathway -- 9. Loqs-PD Functions in the siRNA Pathway -- 10. Loqs-PB Is Required to Maintain Ovarian Germline Stem Cells -- 11. For Some miRNAs, Loqs-PB Tunes Mature miRNA Length -- 12. Future Directions -- 13. Concluding Remarks -- Acknowledgments -- References -- 3. Translin: TRAX Complex (C3PO), a Novel Ribonuclease for the Degradation of Small RNAs / Qinghua Liu -- 1. Introduction: Earlier Studies of Translin and TRAX -- 2. Discovery of C3PO as a Novel Endoribonuclease Involved in the Activation of RNA-Induced Silencing Complex -- 3.C3PO Ribonuclease in tRNA Processing -- 4. Structure of C3PO: An Unusual Asymmetrical Hetero-Octamer -- 5. Oligomeric States of C3PO and Implications for Substrate Binding and Activation -- 6. Enzymatic Properties of C3PO -- 7. Concluding Rem…
  note: edited by Guillaume F. Chanfreau, Fuyuhiko Tamanoi.
  note: Includes bibliographical references and indexes.
  subject:
    topic: Enzymes
  subject:
    topic: Eukaryotic cells
  subject:
    topic: RNA
  subject:
    topic: Enzymes
  subject:
    topic: Eukaryotic cells
  subject:
    topic: RNA
  subject:
    topic: RNA Stability
  subject:
    topic: Organelle Biogenesis
  subject:
    topic: Eukaryotic Cells
  classification: QP601 .E95 2012eb
  classification: 572.88
  classification: QU 300
  related item:
    title info:
      title: Enzymes ; v. 32
  identifier: 9780124047419
  identifier: 0124047416
  identifier: https://www.sciencedirect.com/science/bookseries/18746047/32
  record info:
    record content source: OHS
    record creation date: 121116
    record change date: 20180501122005.0
    record identifier: ocn818369206
    language of cataloging:
      language term: eng