rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Advances in genetics
    part number: Volume 83
  name:
    name part: Friedmann, Theodore
    name part: 1935-
    role:
      role term: editor.
  name:
    name part: Dunlap, Jay C.
    role:
      role term: editor.
  name:
    name part: Goodwin, Stephen F.
    role:
      role term: editor.
  type of resource: text
  genre: Electronic books.
  origin info:
    place:
      place term: ne
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource
  abstract: The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. * Includes methods for testing with ethical, legal, and social implications * Critically analyzes future.
  table of contents: Front Cover; Advances in Genetics; Copyright; Contents; Contributors; Chapter One: Biology and Mechanisms of Short RNAs in Caenorhabditis elegans; 1. Introduction; 2. miRNA Function; 2.1. Biological effects of miRNAs; 2.1.1. Developmental timing; 2.1.2. Embryonic development; 2.1.3. Postembryonic development; 2.1.4. Physiology; 2.1.5. Longevity and stress response; 2.2. Biogenesis and molecular mechanisms of miRNAs; 3. RNAi and Endogenous siRNAs; 3.1. Exogenous RNAi pathway; 3.1.1. RDE-4 and Dicer; 3.1.2. RDE-1 Argonaute protein; 3.1.3. siRNA amplification and additional Argonautes.
  table of contents: 3.1.4. Mutator proteins3.1.5. ABC transporters; 3.1.6. RDE-10/RDE-11 complex; 3.1.7. Transcriptional silencing induced by dsRNA; 3.1.8. Inheritance of dsRNA-induced gene silencing; 3.1.9. Chromatin modulators of the RNAi response; 3.2. Genomic and molecular features of endogenous RNAi; 3.2.1. Discovery of endo-siRNAs; 3.2.2. Distinction between WAGO- and CSR-1-associated 22G-endo-siRNAs; 3.2.3. 26G- and 22G-endo-siRNAs of the ERI pathway; 3.2.4. Competition between ADARs and endogenous RNAi; 3.3. Biological functions of RNAi; 3.3.1. Antiviral defense.
  table of contents: 3.3.2. Silencing of transposons and repetitive elements3.3.3. A summary of the global effects of 22G-RNAs on the expression of endogenous genes; 3.3.4. Endogenous RNAi and adaptation to environment; 3.3.5. Developmental roles of the CSR-1 22G-RNA pathway; 3.3.6. Cooperation between RNAi and Rb; 3.3.7. The role of ALG-3/4 endo-siRNAs in sperm development; 4. 21U-RNAs, C. elegans piRNAs; 4.1. Biogenesis of 21U-RNAs; 4.2. Biological functions of 21U-RNAs; 4.2.1. Function in fertility; 4.2.2. Connection between 21U-RNAs, 22G-RNA production, and stable silencing of foreign DNA.
  table of contents: 5. Systemic Features of RNAi5.1. dsRNA import channel SID-1 and the features of mobile RNA species; 5.2. Additional factors required for systemic and environmental RNAi; 5.2.1. SID-2; 5.2.2. SID-3; 5.2.3. SID-5; 6. Outlook; Acknowledgments; References; Chapter Two: Genetics of Immune Recognition and Response in Drosophila host defense; 1. Introduction; 1.1. Overview of Drosophila immune responses; 2. Toll Signaling in Drosophila; 2.1. Activation; 2.1.1. The Necrotic-Persephone axis; 2.1.2. PGRPs and GNBPs; 2.1.3. Mechanism of sensing bacterial and fungal cell wall components.
  table of contents: 2.1.4. Ligand activation: The role of Spz2.2. Intracellular signaling; 2.3. Host-pathogen interaction upstream of Toll; 3. The Immune Deficiency Pathway; 3.1. Recognition and intracellular signaling; 3.2. Gut immunity and IMD signaling; 3.3. Host-pathogen interaction; 4. Immunity as a Sensor of Metabolism; 5. Concluding Remarks-Future Directions; Acknowledgments; References; Chapter Three: Recent Advances in Septum Biogenesis in Neurospora crassa; 1. Introduction; 2. Septum Ontogeny; 2.1. Septation during hyphal development; 2.2. Septation establishment: Regulators and positional markers.
  note: edited by Theodore Friedmann, Jay Dunlap, Stephen Goodwin.
  subject:
    topic: Genetics
  subject:
    topic: SCIENCE
    topic: Life Sciences
    topic: Genetics & Genomics
  subject:
    topic: Genetics
  classification: QH430
  classification: 576.5
  related item:
    title info:
      title: Advances in genetics. Volume 83
    identifier: (OCoLC)853505664
  identifier: 9780124078017
  identifier: 012407801X
  identifier: 9780124076754
  identifier: 0124076750
  identifier: https://www.sciencedirect.com/science/bookseries/00652660/83
  record info:
    record content source: N$T
    record creation date: 130731
    record change date: 20180501122012.0
    record identifier: ocn854760495
    language of cataloging:
      language term: eng