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Advances in planar lipid bilayers and liposomes
1 online resource (238 pages) : illustrations (some color)
Although the origin and the basic meaning of the terms ""planar lipid bilayers"" and ""liposome"" have not changed during the years, the present advances in the scientific, technological, biomedical and consumer product fields are remarkable. Ever since its launch the ""Adances in Planar Lipid Bilayers and Liposomes' (APLBL) has provided a global platform for a community of researchers having very broad scientific interests in theoretical, experimental and simulation studies on lipid and cell membrane micro and nanostructures. Ranging from artificial lipid membranes to cell membranes.
Front Cover; Advances in Planar Lipid Bilayers and Liposomes; Copyright; Contents; Contributors; Preface; Chapter One: Biomimetic Membrane Supported at a Metal Electrode Surface: A Molecular View; 1. Introduction; 2. sBLM Preparation Methods; 2.1. Vesicle fusion; 2.2. Langmuir-Blodgett and Langmuir-Schaefer deposition; 3. Potential Drop Across the Membrane and an Estimate of the Electric Field Acting on the Membrane; 4. Effect of the Potential Applied to the Gold Electrode on the Membrane Stability: AFM, NR, and Surface-Enhanced Infrared ...
5. Imaging Aggregation of Antibiotic Peptides in a Lipid Membrane6. Potential-Controlled Changes in the Orientation and Conformation of Peptides and Peripheral Proteins: IR Studies of Gra ... ; 7. Summary and Conclusions; Acknowledgment; References; Chapter Two: Lipid Monolayers at the Air-Water Interface: A Tool for Understanding Electrostatic Interactions and Rheology ... ; 1. Introduction; 2. Experimental Approaches on Monolayers; 3. Phase Diagrams: Two-Phase Regions; 4. Distribution of the Phases in the Plane of the Monolayer.
5. In-Plane Interactions and Consequences on Film Effective Rheology6. Comparison Between Different Model Membranes; 7. Summary; Acknowledgments; References; Chapter Three: Langmuir-Blodgett Approach to Investigate Antimicrobial Peptide-Membrane Interactions; 1. Introduction; 2. Target Membrane Architecture; 3. The Role of Phospholipids; 4. Lipid Monolayers; 5. Effect of Phospholipid Packing Characteristics and Lipid Phase Transitions on Membrane Stability; 6. Visualization of Lipid Films; 7. Conclusion; References; Chapter Four: Divalent Metal Cations in DNA-Phospholipid Binding.
1. Introduction2. DNA-Phospholipid-Divalent Metal Cation Interaction; 3. Divalent Metal Cations as a Mediator of DNA-Neutral Phospholipid Bilayer Binding; 3.1. DNA condensation; 3.2. DNA thermal stability; 4. The Structural Variety of DNA-PC-Me2+ Aggregates; 4.1. X-ray diffraction on DNA-DPPC-Me2+ aggregates: Effect of temperature; 4.2. Structural polymorphism of DNA-PC-Me2+ aggregates; 4.3. DNA-DPPC-Zn2+ aggregates; 5. Conclusion; Acknowledgments; References; Chapter Five: Solid-Like Domains in Mixed Lipid Bilayers: Effect of Membrane Lamellarity and Transition Pathway; 1. Introduction.
2. Materials and Methods2.1. Preparation of vesicles; 2.2. Optical microscopy; 2.3. Wide-angle X-ray scattering; 2.4. Differential scanning calorimetry; 3. Results and Discussion; 3.1. Phase behavior: Transition temperatures and structures; 3.2. Shape of solid-like domains; 3.2.1. Effect of transition pathway; 3.2.2. Effect of membrane lamellarity; 4. Summary and Outlook; Acknowledgments; References; Chapter Six: Hexagonal Phase Formation in Oriented DPPC-Melittin Samples: A Small-Angle X-ray Diffraction Study; 1. Introduction; 2. Materials and Methods; 3. Results and Discussion.
edited by Ales Iglic [and three others] ; contributors Paul A. Beales [and twenty two others].
Includes bibliographical references at the end of each chapters and index.
Advances in planar lipid bilayers and liposomes. Volume 20
Waltham, Massachusetts : Academic Press, ©2014