rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Molecular biology of aging
  name:
    name part: Reddy, P. Hemachandra
    role:
      role term: editor.
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: mau
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource
  table of contents: Front Cover; Molecular Biology of Aging; Copyright; Contents; In Memoriam; Contributors; Preface; Chapter One: Clinical Aspects of Glucose Metabolism and Chronic Disease; 1. Introduction; 2. Diabetes Mellitus; 3. Cardiovascular Disease; 4. Chronic Kidney Disease; 5. Sarcopenia; 6. The Frailty Syndrome; 7. Dementia; 8. Exercise and Brain Metabolism; 9. Pharmacological Treatments for Dementia; 10. Reducing Chronic Disease Burden; References; Chapter Two: Therapeutic Strategies for Mitochondrial Dysfunction and Oxidative Stress in Age-Related Metabolic Disorders; 1. Introduction
  table of contents: 2. Global Prevalence of Metabolic Disorders3. Structure and Functions of Mitochondria; 3.1. Mitochondrial Dynamics; 3.2. Mitochondrial Biogenesis; 4. Mitochondrial Dysfunction in Age-Related Metabolic Disorders; 4.1. Type 2 Diabetes Mellitus; 4.2. Obesity; 4.3. Cardiovascular Diseases; 4.4. Stroke; 5. Strategies Directed to Target Mitochondrial Dysfunction; 5.1. Lifestyle Interventions; 5.1.1. Exercise; 5.1.2. Dietary Modifications; 5.2. Pharmacological Interventions; 5.2.1. Mitochondria-Targeted Antioxidants; 5.2.2. Sirtuins; 6. Concluding Remarks; Acknowledgments; References
  table of contents: Chapter Three: MicroRNAs as Peripheral Biomarkers in Aging and Age-Related Diseases1. Introduction; 2. Circulatory miRNAs; 3. miRNAs Secretion in Circulatory Biofluids; 4. Circulatory miRNAs as Biomarkers in Aging and Age-Associated Diseases; 4.1. Aging; 4.2. Cardiovascular Disease; 4.3. Cancer; 4.3.1. Aging and Cancer; 4.3.2. Prostate Cancer; 4.3.3. Lung Cancer; 4.3.4. Breast Cancer; 4.3.5. Colorectal Cancer; 4.4. Arthritis; 4.5. Cataract; 4.6. Osteoporosis; 4.7. Diabetes/Obesity; 4.8. Hypertension; 4.9. Neurodegenerative Diseases; 4.9.1. Dementia; 4.9.2. Alzheimerś Disease
  table of contents: 4.9.2.1. Circulatory miRNAs in Whole Blood4.9.2.2. Blood Mononuclear Cells as a Source of miRNAs; 4.9.2.3. Serum as Sources of Circulatory miRNAs; 4.9.2.4. Serum Exosomal miRNAs; 4.9.2.5. Plasma as Sources of Circulatory miRNAs; 4.9.2.6. Plasma Exosomal miRNAs; 4.9.2.7. CSF and Extracellular Fluid Circulatory miRNAs; 4.9.3. Huntingtonś Disease; 4.9.4. Parkinsonś Disease; 4.9.5. Amyotrophic Lateral Sclerosis; 5. Concluding Remarks; Acknowledgments; References; Chapter Four: Molecular Links and Biomarkers of Stroke, Vascular Dementia, and Alzheimerś Disease; 1. Introduction; 1.1. Stroke
  table of contents: 1.2. Dementia1.2.1. Vascular Dementia; 1.2.2. Alzheimerś Disease; 2. Risk Factors for IS, VaD, and AD; 3. Molecular Links and Pathways; 4. Molecular Biomarkers; 4.1. Protein Biomarkers in Stroke, VaD, and AD; 4.2. miRNAs as Peripheral Biomarkers in Stroke, VaD, and AD; 4.2.1. miRNA Profile and Function in Human Samples; 4.2.2. MiRNA Profile and Function in Animal and Postmortem Brain; 5. Concluding Remarks; Acknowledgments; References; Chapter Five: MicroRNAs, Aging, Cellular Senescence, and Alzheimerś Disease; 1. Introduction; 2. Biogenesis and Regulation of miRNAs
  note: edited by P. Hemachandra Reddy.
  note: Includes bibliographical references and index.
  subject:
    topic: Aging
    topic: Molecular aspects
  subject:
    topic: Aging
  subject:
    topic: MEDICAL / Physiology
  subject:
    topic: SCIENCE / Life Sciences / Human Anatomy & Physiology
  subject:
    topic: Aging
    topic: Molecular aspects
  classification: QP86
  classification: 612.6/7
  related item:
    identifier: (OCoLC)959875085
  related item:
    title info:
      title: Progress in molecular biology and translational science ; v. 146
  identifier: 9780128115336
  identifier: 0128115335
  identifier: 9780128115329
  identifier: 0128115327
  identifier: https://www.sciencedirect.com/science/bookseries/18771173/146
  record info:
    record content source: N$T
    record creation date: 170222
    record change date: 20180501122035.0
    record identifier: ocn973396830
    language of cataloging:
      language term: eng