http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
1 online resource (xiv, 248 pages. : illustrations).
Front Cover; Insect Immunity; Copyright; Contents; Contributors; Preface; References; Chapter One: Insect Antimicrobial Defences: A Brief History, Recent Findings, Biases, and a Way Forward in Evolutionary S ...; 1. Introduction; 1.1. Goals of This Review; 1.2. A Brief History of Insect Antimicrobial Defences; 2. The Canonical Immune Genes: A Brief Review of the Components; 2.1. Recognition; 2.2. Signalling; 2.3. Antimicrobial Peptides; 3. From Flies to General Insights Across Insecta; 3.1. Species Diversity; 3.2. Timescale; 3.3. Bottom-up Studies on Candidate Genes
3.4. Candidate Gene Biases3.5. Example for Possible New Insights; 3.6. Epistasis: On the Importance of Genetic Backgrounds; 3.7. Genome-Wide Top-Down Studies Reveal Novel Insights; 3.8. Antibacterial Function of the Cuticle and Peritrophic Matrix; 3.9. Haemocyte Insights: The Early Start of Insect Immunology; 3.10. The Immune Function of Haemolymph Clots; 4. Conclusion; Acknowledgements; References; Chapter Two: Phagocytosis in Insect Immunity; 1. Introduction; 2. Insect Blood Cells; 3. Phagocytic Receptors in Insects; 3.1. Scavenger Receptors; 3.2. Nimrod Receptor Superfamily
3.3. Peptidoglycan-Recognition Receptors Important for Phagocytosis3.4. Integrins; 3.5. Down Syndrome Adhesion Molecule 1 (Dscam 1); 3.6. Opsonins in Insect Phagocytosis; 4. Regulation of Signalling During Phagocytosis; 5. Phagosome Maturation; 6. Conclusion; References; Chapter Three: The Melanization Response in Insect Immunity; 1. Introduction; 2. Melanin Biosynthesis Pathways in Insects; 3. PPO Activation Pathways in Model Insects; 3.1. Drosophila melanogaster; 3.2. Manduca sexta; 3.3. Tenebrio molitor; 3.4. Anopheles gambiae; 3.5. Aedes aegypti
4. The Contribution of the Melanization Response to Insect Immune Defence5. Crosstalk Between Melanization and Other Immune Pathways; 5.1. Melanization and AMP Synthesis; 5.2. Melanization and Complement Pathway; 6. Concluding Remarks; References; Chapter Four: Microbiota, Gut Physiology, and Insect Immunity; 1. Introduction; 2. Gut Structure and Gut Microbes; 2.1. Gut Structure and Function; 2.2. The Microbial Environment of the Gut Epithelium; 2.2.1. Gut Pathogens; 2.2.2. Gut Microbiota; 3. Gut Immunity; 3.1. The IMD Pathway; 3.1.1. Positive and Negative Regulation of Intestinal IMD Pathway
3.1.2. Physiological Roles of the Intestinal IMD Pathway3.2. The DUOX Pathway; 3.2.1. DUOX in Gut Immunity; 3.2.2. Uracil as a DUOX-Activating Bacterial Ligand; 3.2.3. Complex Regulation of Signal Pathways Leading to DUOX Activation; 4. Gut Renewal; 4.1. ISC Self-Renewal, Differentiation, and Proliferation; 4.2. Gut Renewal and Innate Immune Systems; 5. Concluding Remarks; Acknowledgements; References; Chapter Five: Intestinal Stem Cells: A Decade of Intensive Research in Drosophila and the Road Ahead; 1. Introduction; 2. The Evolutionary Origin of ISCs; 3. Primary Reports on Drosophila ISCs
SCIENCE / Life Sciences / Zoology / General