rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Nanomedicine in Central Nervous System Injury and Repair
  name:
    name part: Sharma, H. S. (Hari Shanker)
    role:
      role term: editor.
  name:
    name part: Sharma, Aruna
    role:
      role term: editor.
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: mau
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xv, 165 pages : illustrations).
  abstract: Nanomedicine in Central Nervous System Injury and Repair (IRN), Volume 137, the latest release in the International Review of Neurobiology series presents comprehensive chapters that cover a broad range of topics, including, but not limited to, how Diabetes exacerbates methamphetamine induced blood-brain barrier breakdown, edema formation, oxidative stress and myelin damage, and how Focal blast brain injury induces rapid edema formation, blood-brain barrier breakdown and intensive cellular damage. In addition, the Neuroprotective effects of a multimodal drug cerebrolysin are explored, as is how Nanowired cerebrolysin potentiates neuroprotective effects of histamine H3 receptor inverse agonist and antagonist with partial H4 agonist in Alzheimer's Disease. This series reviews current knowledge and understanding on how to repair the damaged spinal cord and brain with nanomedicine, detailing new therapeutic advances and providing a starting point for researchers and practitioners entering the field.
  table of contents: ""Front Cover""; ""Nanomedicine in Central Nervous System Injury and Repair""; ""Copyright""; ""Contents""; ""Contributors""; ""Preface""; ""References""; ""Acknowledgments""; ""Chapter One: Current Strategies for the Delivery of Therapeutic Proteins and Enzymes to Treat Brain Disorders""; ""1. Introduction""; ""2. Physical Delivery""; ""3. Nonphysical Methods""; ""3.1. Systemic Delivery""; ""3.2. In Vitro Targeting""; ""3.3. In Vivo Proteins, Fusion Proteins, and Modified Enzymes""; ""3.4. Nanoparticle-Based Delivery""; ""4. Conclusion""; ""References""
  table of contents: ""Chapter Two: Impact of Inflammation on the Blood-Neural Barrier and Blood-Nerve Interface: From Review to Therapeutic Preview""""1. Introduction""; ""2. Blood-Nerve Interface""; ""3. Mast Cells and the BBB""; ""4. Immune Cell Interactions Amplify Neuroinflammation""; ""5. Neuroinflammation and Aging""; ""6. Mast Cells and Glia as Therapeutic Targets""; ""7. Conclusion and Perspectives""; ""Acknowledgments""; ""Conflict of Interest""; ""References""; ""Chapter Three: Intravenous Administration of Functionalized Magnetic Iron Oxide Nanoparticles Does Not Induce CNS Injury ...""
  table of contents: ""1. Introduction""""1.1. Magnetic Iron Oxide Nanoparticles""; ""1.2. Polymer-Coated Iron Oxide Nanoparticles""; ""1.3. Superparamagnetic Iron Oxide Nanoparticles""; ""2. Experimental Procedures""; ""3. SCI Model""; ""4. Nanoparticle Administration""; ""5. Treatment With Cerebrolysin""; ""5.1. Blood-Spinal Cord Barrier/BBB Permeability""; ""5.2. Edema Formation""; ""5.3. Morphological Changes in the Cord""; ""5.4. Experimental Observations""; ""5.4.1. Iron Oxide Nanoparticles Effect on BSCB/BBB Permeability""; ""5.4.2. Morphological Changes Inside the Cord""
  table of contents: ""6. Effects of Cerebrolysin on BBB/BSCB Permeability""""6.1. Effects of Cerebrolysin on Neuronal and Glial Cell Damage""; ""6.2. Probable Mechanisms of IOMNP-Induced Neurotoxicity""; ""6.3. Cerebrolysin-Induced Neuroprotection""; ""7. Conclusion and Future Perspectives""; ""Acknowledgments""; ""References""; ""Chapter Four: Histaminergic Receptors Modulate Spinal Cord Injury-Induced Neuronal Nitric Oxide Synthase Upregulation and ...""; ""1. Introduction""; ""2. Histamine in the Spinal Cord""; ""3. Histamine and Nitric Oxide Interaction""
  table of contents: ""4. Histamine and the Spinal Cord Microcirculation""""5. Histamine and the BSCB Permeability""; ""6. Histamine and Spinal Cord Edema""; ""7. Nanowired Drug Delivery Enhances Neuroprotection""; ""8. Our Investigations on Histamine-Receptor Modulation and nNOS Expression in SCI""; ""8.1. Animals""; ""8.2. Spinal Cord Injury""; ""8.3. Drug Treatments""; ""8.4. TiO2-Nanowired Delivery of Cimetidine and Ranitidine""; ""8.5. Parameters Measured""; ""8.6. BSCB Permeability""; ""8.7. Spinal Cord Edema""; ""8.8. Spinal Cord Blood Flow""; ""8.9. Morphological Analyses""
  note: edited by Hari S. Sharma, Aruna Sharma.
  note: Text in English.
  note: Includes bibliographical references.
  subject:
    topic: Nanomedicine
  subject:
    topic: Central nervous system
    topic: Wounds and injuries
  subject:
    topic: HEALTH & FITNESS / Holism
  subject:
    topic: HEALTH & FITNESS / Reference
  subject:
    topic: MEDICAL / Alternative Medicine
  subject:
    topic: MEDICAL / Atlases
  subject:
    topic: MEDICAL / Essays
  subject:
    topic: MEDICAL / Family & General Practice
  subject:
    topic: MEDICAL / Holistic Medicine
  subject:
    topic: MEDICAL / Osteopathy
  subject:
    topic: Central nervous system
    topic: Wounds and injuries
  subject:
    topic: Nanomedicine
  subject:
    topic: Nanomedicine
  subject:
    topic: Central Nervous System
    topic: injuries
  classification: R857.N34
  classification: RC341 .I5 v.137eb
  classification: 610.28
  related item:
    identifier: (OCoLC)992451100
  related item:
    title info:
      title: International review of neurobiology ; v. 137
  identifier: 9780128123829
  identifier: 0128123826
  identifier: 9780128123812
  identifier: 0128123818
  identifier: https://www.sciencedirect.com/science/bookseries/00747742/137
  record info:
    record content source: N$T
    record creation date: 171114
    record change date: 20180501122038.0
    record identifier: on1011496897
    language of cataloging:
      language term: eng