rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Chemical and Biochemical Approaches for the Study of Anesthetic Function
    part name: Part A
  name:
    name part: Eckenhoff, Roderic G.
    role:
      role term: editor.
  name:
    name part: Dmochowski, Ivan J.
    role:
      role term: editor.
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: mau
    date issued: 2018
    edition: First edition.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource.
  abstract: "Chemical and Biochemical Approaches for the Study of Anesthetic Function, Part A, Volume 602 assembles new information on our understanding of anesthesia. This latest release in the series includes sections on how physical accuracy leads to biological relevance, best practices for simulating ligand-gated ion channels interacting with general anesthetics, computational approaches for studying voltage-gated ion channels modulation by general anesthetics, anesthetic parameterization, pharmacophore QSAR, QM, ONIOM, and kinetic modeling of electrophysiology data. We have selected the primary experts to write about each approachThis provides one-stop shopping for all the means of addressing this complex questionAnesthesia is enormously important as almost everybody receives it at some point"--
  table of contents: Part A: Chapter One: Physical Accuracy Leads to Biological Relevance: Best Practices For Simulating Ligand-Gated Ion Channels Interacting with General Anesthetics / Sruthi Murlidaran, Grace Brannigan -- Chapter Two: Computational Approaches to Studying Voltage-Gated Ion Channel Modulation by General Anesthetics / Eleonora Gianti, Vincenzo Carnevale -- Chapter Three: Molecular Mechanics Parameterization of Anesthetic Molecules / Thomas T. Joseph, Jérôme Hénin -- Chapter Four: Insights Into Receptor-Based Anesthetic Pharmacophores and Anesthetic-Protein Interactions / Victoria S. Fahrenbach, Edward J. Bertaccini -- Chapter Five: Understanding Anesthetic Mechanisms: Analysis of the Complex Kinetics of Ligand-Gated Ion Channels / Robert S. Cantor -- Chapter Six: General Genetic Strategies / Louise M. Steele, Philip G. Morgan -- Chapter Seven: Approaches to Anesthetic Mechanisms: The C. elegans Model / Louise M. Steele, Margaret M. Sedensky -- Chapter Eight: Using Drosophila to Understand General Anesthesia: From Synapses to Behavior / Shanker Karunanithi, Michael Troup, Bruno van Swinderen -- Chapter Nine: High-Throughput Screening to Identify Anesthetic Ligands Using Xenopus laevis Tadpoles / Kellie A. Woll, Roderic G. Eckenhoff -- Chapter Ten: Zebrafish: A Pharmacogenetic Model for Anesthesia / Victoria Bedell, Elena Buglo, Daniel Marcato, Christian Pylatiuk, Ralf Mikut, Johannes Stegmaier, Will Scudder, Maxwell Wray, Stephan Zuchner, Uwe Strahle, Ravindra Peravali, and Julia E. Dallman -- Chapter Eleven: The Mouse as a Model Organism for Assessing Anesthetic Sensitivity / Andrzej Z. Wasilczuk, Kaitlyn L. Maier, Max B. Kelz -- Chapter Twelve: Identification of General Anesthetic Target Protein-Binding Sites by Photoaffinity Labeling and Mass Spectrometry / Kellie A. Woll, William P. Dailey, Roderic G. Eckenhoff -- Chapter Thirteen: Xenon-Protein Interactions: Characterization by X-Ray Crystallography and Hyper-CEST NMR / Benjamin W. Roose, Serge D. Zemerov, Ivan J.…
  table of contents: Part B: Chapter One: Structural Analysis of Anesthetics in Complex with Soluble Proteins / Patrick J. Loll -- Chapter Two: X-Ray Crystallographic Studies for Revealing Binding Sites of General Anesthetics in Pentameric Ligand-Gated Ion Channels / Qiang Chen, Yan Xu, Pei Tang -- Chapter Three: Solution NMR Studies of Anesthetic Interactions with Ion Channels / Vasyl Bondarenko, Marta Wells, Yan Xu, Pei Tang -- Chapter Four: Time-Resolved Neutron Interferometry and the Mechanism of Electromechanical Coupling in Voltage-Gated Ion Channels / J. Kent Blasie -- Chapter Five: Fluorescent Anesthetics / Daniel J. Emerson, Ivan J. Dmochowski -- Chapter Six: Investigation of Anesthetic-Protein Interactions by a Thermodynamic Approach / Hasan Babazada, Renyu Liu -- Chapter Seven: Electron Spin Resonance (EPR) in Drosophila and General Anesthesia / Luca Turin, Efthimios M.C. Skoulakis -- Chapter Eight: Giant Plasma Membrane Vesicles: An Experimental Tool for Probing the Effects of Drugs and Other Conditions on Membrane Domain Stability / Zoe Gerstle, Rohan Desai, Sarah L. Veatch -- Chapter Nine: Anesthetic Drug Discovery and Development: A Case Study of Novel Etomidate Analogs / Megan McGrath, Douglas E. Raines -- Chapter Ten: Optoanesthesia: Use of Anesthetic Photolabels In Vivo / Andrew R. McKinstry-Wu, Max B. Kelz -- Chapter Eleven: Optogenetics and Chemogenetics / Ksenia Vlasov, Christa J. Van Dort, Ken Solt -- Chapter Twelve: Genetic Reporters of Neuronal Activity: c-Fos and G-CaMP6 / Andrew E. Hudson -- Chapter Thirteen: Genomics and Proteomic Techniques / Jonathan Z. Pan -- Chapter Fourteen: Neurochemistry of Anesthetic States / Ralph Lydic, Helen A. Baghdoyan, Amanda L. May -- Chapter Fifteen: Brief Introduction to Electroencephalography / Alex Proekt -- Chapter Sixteen: Using Positron Emission Tomography in Revealing the Mystery of General Anesthesia: Study Design Challenges and Opportunities / Harry Scheinin, Emilee C. Alkire, Annalotta Scheinin, Michael T. Alkire, Osk…
  note: edited by Roderic G. Eckenhoff, Ivan J. Dmochowski.
  note: Includes bibliographical references.
  subject:
    topic: Anesthetics
    topic: Mechanism of action
  subject:
    topic: Anesthetics
    topic: Physiological effect
  subject:
    topic: MEDICAL
    topic: Surgery
    topic: General
  subject:
    topic: Anesthetics
    topic: Mechanism of action
  subject:
    topic: Anesthetics
    topic: Physiological effect
  subject:
    topic: Anesthetics
  classification: RD85.5
  classification: 617.9/67
  classification: QV 81
  related item:
    title info:
      title: Chemical and Biochemical Approaches for the Study of Anesthetic Function. Part A
    origin info:
      publisher: Cambridge, MA : Academic Press, an imprint of Elsevier, 2018
      edition: First edition.
    identifier: (OCoLC)1013498799
  related item:
    title info:
      title: Methods in enzymology ; v. 602
  identifier: 9780128127414
  identifier: 0128127414
  identifier: 9780128127407
  identifier: 0128127406
  identifier: https://www.sciencedirect.com/science/bookseries/00766879/602
  record info:
    record content source: N$T
    record creation date: 180329
    record change date: 20200326101152.0
    record identifier: on1029759661
    language of cataloging:
      language term: eng