rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Mitochondria and longevity
  name:
    name part: López-Otín, Carlos
    role:
      role term: editor.
  name:
    name part: Galluzzi, Lorenzo
    role:
      role term: editor.
  type of resource: text
  genre: Electronic books.
  origin info:
    place:
      place term: xx
    date issued: 2018
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource
  table of contents: Front Cover; International Review of Cell and Molecular Biology; INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY; INTERNATIONAL REVIEW OFCELL AND MOLECULAR BIOLOGY: Mitochondria and Longevity; Contents; CONTRIBUTORS; One -- Mitochondrial Metabolism and Aging in Yeast; 1. INTRODUCTION; 2. THE TRICARBOXYLIC ACID CYCLE; 3. TRICARBOXYLIC ACID CYCLE DYSFUNCTIONS AND AGING; 4. IMPAIRED MITOCHONDRIAL PYRUVATE/ACETYL-COA METABOLISM AND AGING; 5. MITOCHONDRIAL METABOLISM OF BRANCHED-CHAIN AMINO ACIDS AND AGING; 6. THE OXIDATIVE PHOSPHORYLATION
  table of contents: 7. RESPIRATION, ROS PRODUCTION AND AGING: A COMPLEX INTERPLAY7.1 Complex I; 7.2 Complex II; 7.3 Complex III; 7.4 Complex IV; 7.5 F1FO ATPase; 8. ROLE OF NAD+ METABOLISM IN MITOCHONDRIAL FUNCTIONALITY; 9. NAD+ METABOLISM AND AGING; 10. NAD+ IS A KEY MODULATOR OF PATHWAYS INVOLVED IN THE AGING PROCESS; 11. CONCLUSIONS; ACKNOWLEDGMENTS; REFERENCES; Two -- Mitohormesis, an Antiaging Paradigm; 1. INTRODUCTION; 2. MITONUCLEAR COMMUNICATION; 3. MITOHORMESIS SIGNALING; 3.1 Reactive Oxygen Species; 3.2 Mitochondrial Ions and Metabolites; 3.3 Proteotoxic Signals
  table of contents: 3.4 Mitochondria-Cytosol Stress Responses3.4.1 Translational Stress Response; 3.4.2 Post-translational Stress Responses; 3.5 Mitokines; 4. MITOHORMESIS AND LIFESPAN; 5. MITOHORMESIS AND HEALTHSPAN; 6. CONCLUDING REMARKS AND FUTURE OUTLOOK; REFERENCES; Three -- Coordinating Mitochondrial Biology Through the Stress-Responsive Regulation of Mitochondrial Proteases; 1. INTRODUCTION; 1.1 Organization and Activity of the Mitochondrial Proteolytic Network; 1.1.1 Processing Peptidases Facilitate Establishment of the Mitochondrial Proteome
  table of contents: 1.1.2 Mitochondrial Quality Control Proteases Regulate the Integrity and Function of the Mitochondrial Proteome1.1.3 Oligopeptidases Degrade Polypeptides Within Mitochondria; 1.2 Mitochondrial Proteases Are Key Regulators of Organellar Quality Control; 1.2.1 Mitochondrial Morphology Is Regulated by the Activity of Mitochondrial Proteases; 1.2.2 Proteolytic Control of Mitophagy; 1.3 Mitochondrial Proteases Link Mitochondrial Proteostasis to Apoptotic Signaling; 1.4 Stress-Responsive Regulation of the Mitochondrial Proteolytic Network
  table of contents: 1.4.1 Mitochondrial Unfolded Protein Response-Dependent Regulation of Mitochondrial Proteostasis1.4.2 The Integrated Stress Response Coordinates Mitochondrial Proteostasis in Response to Diverse Insults; 1.4.3 LON Is Also Transcriptionally Regulated by Other Stress-Responsive Signaling Pathways; 1.4.4 Posttranslational Regulation of Mitochondrial Proteolytic Activity; 1.5 Altered Mitochondrial Protease Activity in Aging and Disease; 1.5.1 Mutations in Mitochondrial Proteases Are Genetically Linked to Diverse Neurodegenerative Disorders
  note: edited by Carlos López-Otín, Lorenzo Galluzzi.
  note: Title from title details screen.
  subject:
    topic: Mitochondria
  subject:
    topic: Aging
    topic: Molecular aspects
  subject:
    topic: SCIENCE
    topic: Life Sciences
    topic: Anatomy & Physiology
  subject:
    topic: Aging
    topic: Molecular aspects
  subject:
    topic: Mitochondria
  classification: QH603.M5
  classification: 571.6/57
  related item:
    title info:
      title: Mitochondria and longevity
    origin info:
      publisher: [Place of publication not identified] : Academic Press, an imprint of Elsevier, 2018
    identifier: (OCoLC)1020025171
  related item:
    title info:
      title: International review of cell and molecular biology ; v. 340
  identifier: 9780128157374
  identifier: 0128157372
  identifier: 9780128157367
  identifier: 0128157364
  identifier: https://www.sciencedirect.com/science/bookseries/19376448/340
  record info:
    record content source: N$T
    record creation date: 180807
    record change date: 20200326101154.0
    record identifier: on1047959806
    language of cataloging:
      language term: eng