rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Membranes in Pulmonary Vascular Disease
  name:
    name part: Belvitch, Patrick
    role:
      role term: editor.
  name:
    name part: Dudek, Steven
    role:
      role term: editor.
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: mau
    date issued: 2018
    edition: First edition.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource : illustrations
  abstract: Membranes in Pulmonary Vascular Disease, Volume 82, the latest release in the Current Topics in Membranes series, highlights new advances in the field, with this new volume presenting interesting chapters from recognized experts on topics such as Sphingolipids in Vascular Lung Disease, Endothelial Glycocalyx, Cholesterol Regulation of Endothelial Cell Calcium Homeostasis in Pulmonary Hypertension, Mechanosensitive Channels and Gap Junction Channels in EC, Endothelial Protrusions in Junctional Integrity and Barrier Function, Cortical Actin Dynamics in Endothelial Permeability, Endothelial Microparticles and Exosomes, Store Operated TRP Channels and Endothelial Responses, and Caveolin and Endothelial NO signaling.
  table of contents: Front Cover; Membranes in Pulmonary Vascular Disease; Copyright; Contents; Contributors; Preface; Chapter One: Sphingolipids Signaling in Lamellipodia Formation and Enhancement of Endothelial Barrier Function; 1. Introduction; 2. Dynamics of Lamellipodia; 3. Modulation of Lung Endothelial Barrier Function by Inflammatory and Protective Agents; 4. Mechanisms of Lamellipodia Formation and Endothelial Barrier Enhancement; 4.1. Sphingosine Kinase/Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptors Signaling and Focal Adhesions in Barrie ...
  table of contents: 4.2. S1P Analogs, FTY720, FTY720-P, and FTY-720 Phosphonate, and Endothelial Barrier Enhancement4.3. HGF/c-Met/PI3K/Akt Signaling in Lamellipodia Formation and Endothelial Barrier Enhancement; 4.4. Cross-Talk Between HGF/c-Met and SPHK1/S1P/S1PR Signaling in Lamellipodia Formation and Endothelial Barrier Enhancement; 5. Reactive Oxygen Species, Lamellipodia Formation, and Endothelial Barrier Enhancement; 6. Oxidized Phospholipids, Lamellipodia Formation, and Endothelial Barrier Enhancement; 7. Simvastatin Activation of S1P1 in Endothelial Barrier Enhancement
  table of contents: 8. Conclusions and Future DirectionsAcknowledgments; References; Chapter Two: The Pulmonary Endothelial Glycocalyx in ARDS: A Critical Role for Heparan Sulfate; 1. Emerging Understanding and Historical Underappreciation of Endothelial Glycocalyx Structure and Function; 2. Polysaccharide Structure of the Endothelial Glycocalyx: A Focus on HeparanSulfate; 3. Pulmonary Endothelial Glycocalyx Heparan Sulfate Is Essential for Lung Homeostasis; 4. Fate of Glycocalyx Heparan Sulfate During Sepsis-Induced ARDS Onset and Resolution
  table of contents: 4.1. Sepsis-Associated Pulmonary Endothelial Glycocalyx Degradation Mediates Lung Injury Onset4.2. Sepsis-Associated Impairment of Heparan Sulfate Reconstitution Prolongs Lung Injury After Sepsis; 5. Multisystemic Consequences of Glycocalyx Degradation; 5.1. Multisystemic Effects of Heparanase Induction; 5.2. Multisystemic Effects of Heparan Sulfate Fragments Released During Glycocalyx Degradation; 6. Unanswered Questions: The Endothelial Glycocalyx in Direct vs. Indirect LungInjury; 7. Summary; References; Chapter Three: Cholesterol Regulation of Pulmonary Endothelial Calcium Homeostasis
  table of contents: 1. Introduction2. Endothelial Ca Channels in the Pulmonary Circulation; 2.1. Functional Roles of Ca in Pulmonary Endothelium; 2.2. Modes of Pulmonary Endothelial Ca Entry; 2.2.1. Store-Operated Ca Entry; 2.2.2. Receptor-Operated Ca Entry; 2.2.3. Depolarization-Induced Ca Entry; 3. Hypoxic Regulation of Pulmonary Endothelial Ca Entry; 4. Role of Membrane Cholesterol in Regulating Endothelial Ca Entry in CH-Induced PH; 4.1. CH Impairs Endothelial Ca Influx by Reducing Membrane Cholesterol; 4.2. Role of Caveolin-1 in Regulating Endothelial Ca Entry
  note: edited by Patrick Belvitch, Steven Dudek.
  note: Includes bibliographical references.
  subject:
    topic: Lungs
    topic: Blood-vessels
    topic: Diseases
  subject:
    topic: Membranes (Biology)
  subject:
    topic: Pulmonary Circulation
  subject:
    topic: HEALTH & FITNESS
    topic: Diseases
    topic: General
  subject:
    topic: MEDICAL
    topic: Clinical Medicine
  subject:
    topic: MEDICAL
    topic: Diseases
  subject:
    topic: MEDICAL
    topic: Evidence-Based Medicine
  subject:
    topic: MEDICAL
    topic: Internal Medicine
  subject:
    topic: Lungs
    topic: Blood-vessels
    topic: Diseases
  subject:
    topic: Membranes (Biology)
  classification: QH601 .C84 2018
  classification: RC776.V37
  classification: 616.24
  related item:
    title info:
      title: Membranes in Pulmonary Vascular Disease
    origin info:
      publisher: Cambridge, MA : Academic Press, 2018
      edition: First edition.
    identifier: (OCoLC)1032024913
  related item:
    title info:
      title: Current topics in membranes ; v. 82
  identifier: 9780128158074
  identifier: 0128158077
  identifier: 9780128158067
  identifier: 0128158069
  identifier: https://www.sciencedirect.com/science/bookseries/10635823/82
  record info:
    record content source: N$T
    record creation date: 181026
    record change date: 20200326101156.0
    record identifier: on1059124556
    language of cataloging:
      language term: eng