Growth factors and receptors : a practical approach /

• Άλλοι συγγραφείς: McKay, I. A. (Ian A.) (επιμελητής.), Brown, K. D. (Kenneth D.) (επιμελητής.)
• Μορφή: Βιβλίο
• Γλώσσα: English
• Έκδοση: Oxford [England] ; New York Oxford University Press, 1998.
• Σειρά: The practical approach series 194.
• Θέματα: Γενετική μηχανική; Γονιδιακή θεραπεία > Έρευνα

Πίνακας περιεχομένων:

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• 1. Engineered growth factors and receptors, and their applications
• 2. Engineering of novel neurotrophins
• 3. Designing new agonists.antagonists of growth factor receptors - the rational design of a super-antagonist of the IL-6 receptor
• 4. A Chimeric approach for studying receptor-binding domains in EGF-like molecules
• 5. Structure-activity relationships of chemokines
• 6. Generation and selection of RNA ligands that inhibit interaction of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) to its receptor
• 7. Immunolocalisation and RT-PCR for detection and quantification of growth factor and gene expression
• 8. Defining growth factor function through tissue-specific expression of dominant-negative receptor mutants
• 9. Growth factor-toxin chimeras and their applications
• 10. Gene therapy applications of growth factors
• Appendix 1
• Appendix 2
• Appendix 3.