Nuclear receptors : a practical approach /

• Other Authors: Picard, Didier
• Format: eBook
• Language: English
• Published: New York : Oxford University Press, 1999.
• Series: Practical approach series ; 207.
• Subjects: Steroid hormones > Receptors.; Nuclear receptors (Biochemistry); Transcription factors.; SOCIAL SCIENCE > Anthropology > Physical.; Receptors, Cytoplasmic and Nuclear.; Receptors, Steroid.; Biochimie.; Hormones st�eroides > R�ecepteurs.; Facteurs de transcription.; Transcription Factors.; Electronic books.; Laboratory Manuals.

The steroid / nuclear receptor superfamily is a large and growing group of transcription factors that are studied by a large and varied number of basic and clinical researchers. The first two chapters describe the evolutionary biology of the superfamily and explain how to clone and characterize new...

Table of Contents:

• Machine generated contents note: 1. Evolutionary biology of the nuclear receptor superfamily / M. Robinson / H. Escriva / V. Laudet
• 2. Initial characterization of new orphan receptors / R. Sladek / V. Giguere
• 3. Adopting orphans: finding ligands / W. Wahli / S. Kersten
• 4. Kinetic analysis of nuclear receptor interactions / L.P. Freedman / B.J. Cheskis
• 5. Functional characterization of co-activators using mammalian cell microinjection / T.-M. Mullen / M.G. Rosenfeld / [and others] / D.W. Rose
• 6. Analysis of steroid/nuclear receptor phosphorylation / N.L. Weigel / B.G. Rowan
• 7. Ligand- and cofactor-regulated transcription with chromatin templates / W.L. Kraus / J.T. Kadonaga
• 8. Hormone-resistance syndromes / M. Gurnell / V.K.K. Chatterjee
• 9. In vitro assembly of steroid receptor
• Hsp90 complexes / D.F. Smith
• 10. Yeast as a system for the study of nuclear receptor function / M.J. Garabedian / J.A. Iniguez-Lluhi / A. Kralli
• 11. Regulation of heterologous proteins by fusion to a hormone binding domain / D. Picard.