Cancer Gene Therapy Past Achievements and Future Challenges /

With the coming of the new millennium we are witnessing a revolution in our understanding of cancer genetics. These are very exciting times. Today we have at our disposal the technology to diagnose abnormalities in our cancer genes and the means to correct the deficit and very soon we will have the...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Habib, Nagy A. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Boston, MA : Springer US, 2002.
Σειρά:Advances in Experimental Medicine and Biology, 465
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • The Clinical Problem
  • Management Problems in Oncology
  • Vectors
  • Adenoviral Vectors
  • Retrovirus Vectors
  • Targetable Gene Delivery Vectors
  • Human ?-fetoprotein Transcriptional Regulatory Sequences
  • Tumor-Targeted Salmonella
  • Mutant Adenoviruses Selectively Replication-Competent in Tumor Cells
  • Polyoma and Papilloma Virus Vectors For Cancer Gene Therapy
  • Cochleates
  • The Use Of Skeletal Muscle To Express Genes For The Treatment Of Cancer
  • Cell Cycle Control
  • Adhesion Molecules in Cancer Biology
  • Cell Cycle Control
  • Apoptosis
  • Killer/DR5, A Novel DNA-Damage Inducible Death Receptor Gene, Links the p53-Tumor Suppressor to Caspase Activation and Apoptotic Death
  • Apoptin®
  • Adenovirus-Mediated Herpes Simplex Thymidine Kinase Gene Therapy For Brain Tumors
  • Development of Clinical Trial of E1A Gene Therapy Targeting HER-2/neu-overexpressing Breast and Ovarian Cancer
  • Tumout Suppressor Genes
  • Pre-clinical Studies with Tumor Suppressor Genes
  • Gene Therapy for Liver Tumours
  • Adenovirus-mediated Transfer of a p53 Gene in Ovarian Cancer
  • Other Systems
  • Eliciting Hyperacute Rejection as a Tumor Killing Strategy
  • Innate Immune Therapy For Cancer
  • Mda-7, A Novel Melanoma Differentiation Associated Gene with Promise for Cancer Gene Therapy
  • Antisense and Ribozymes
  • Antisense IGF and Antisense IGF-IR Therapy of Malignancy
  • Sensitization of Tumors to Chemotherapy Through Gene Therapy
  • Design and Testing of Ribozymes for Cancer Gene Therapy
  • Ribozymes
  • The Approach of Triple Helix Formation in Control of Gene Expression and The Treatment of Tumors Expressing IGF-I
  • Immuno-Modulation
  • Dendritic Cell-based Immunization for Cancer Therapy
  • Hybrid Cell Vaccination for Cancer Immunotherapy
  • Modulation of the Immune Response Through 4-1BB
  • Heat Shock Proteins in Cancer Therapy
  • Bi-Specific Antibodies in Cancer Therapy
  • B7.1 and Cytokines
  • Intralesional Vaccinia/GM-CSF Recombinant Virus in the Treatment of Metastatic Melanoma
  • Suicidal Genes
  • Approaches to Gene-Directed Enzyme Prodrug Therapy (GDEPT)
  • Suicide Gene Therapy
  • Adenoviruses as Gene Delivery Vectors
  • Angiogenesis Control
  • Evaluation of an Inhibitor of DNA Methylation, 5-aza-2?-Deoxycytidine, for The Treatment of Lung Cancer and the Future Role of Gene Therapy
  • Vascular Endothelial Growth Factor as a Target for Cancer Gene Therapy
  • Adeno-Associated Virus and Other Potential Vectors for Angiostatin and Endostatin Gene Therapy
  • Matrix Metallo Proteinase
  • Potential Applications of Tissue Inhibitor of Metalloproteinase (TIMP) Overexpression For Cancer Gene Therapy.