Integration of Pharmaceutical Discovery and Development Case Histories /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Borchardt, Ronald T. (Editor), Freidinger, Roger M. (Editor), Sawyer, Tomi K. (Editor), Smith, Philip L. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US, 1998.
• Series: Pharmaceutical Biotechnology, 11
• Subjects: Life sciences.; Biochemistry.; Animal physiology.; Life Sciences.; Animal Physiology.; Biochemistry, general.

In the late 1980s, it became painfully evident to the pharmaceutical industry that the old paradigm of drug discovery, which involved highly segmented drug - sign and development activities, would not produce an acceptable success rate in the future. Therefore, in the early 1990s a paradigm shift oc...