Multichain Immune Recognition Receptor Signaling From Spatiotemporal Organization to Human Disease /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Sigalov, Alexander B. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York, 2008.
• Σειρά: Advances in Experimental Medicine and Biology, 640
• Θέματα: Medicine.; Oncology.; Life sciences.; Medicine & Public Health.; Biomedicine general.; Life Sciences, general.

Πίνακας περιεχομένων:

• MIRRs: Structure and Physiological Function
• T-Cell Receptor
• B-Cell Receptor
• Fc Receptors
• Natural Killer Cell Receptors
• Platelet Glycoprotein VI
• MIRR Signaling: Possible Mechanisms and the Techniques to Study and Visualize
• Clustering Models
• Segregation Models
• Kinetic Proofreading Model
• Serial Triggering Model
• Conformational Model
• Permissive Geometry Model
• Signaling Chain Homooligomerization (SCHOOL) Model
• Visualization of Cell-Cell Interaction Contacts-Synapses and Kinapses
• Visualization of Protein Interactions in Living Cells
• MIRR Signaling and Therapy of Immune Disorders
• Immunogenicity in Peptide-Immunotherapy: From Self/Nonself to Similar/Dissimilar Sequences
• Therapeutic Application of Transmembrane T and Natural Killer Cell Receptor Peptides
• Fc Receptor Targeting in the Treatment of Allergy, Autoimmune Diseases and Cancer
• Therapeutic Blockade of T- Cell Antigen Receptor Signal Transduction and Costimulation in Autoimmune Disease
• MHC and MHC-Like Molecules: Structural Perspectives on the Design of Molecular Vaccines
• SCHOOL Model and New Targeting Strategies
• Immune Receptor Signaling, Aging and Autoimmunity
• Viral Pathogenesis, Modulation of Immune Receptor Signaling and Treatment.