Pulmonary Biology in Health and Disease

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Bittar, E. Edward (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York, 2002.
• Θέματα: Life sciences.; Human physiology.; Animal physiology.; Biophysics.; Biological physics.; Life Sciences.; Life Sciences, general.; Animal Physiology.; Biophysics and Biological Physics.; Human Physiology.

 Pulmonary Biology in Health and Disease was conceived as a companion to a handful of expensive, multivolume textbooks. This is part of the promising trend to publish shorter textbooks on the subjects of lung biology and remodeling. Whoever is familiar with human biology and the far-reaching consequences of the genome and postgenome revolutions is apt to concede that the centerpiece in remodeling lies in the ?eld of m- ecular cardiobiology. The ?eld of molecular cardiobiology includes the syndrome of chronic heart failure as well as ischemic cardioprotection. By analogy, the centerpiece in pulmonobiology is chronic asthma. Key topics in the present volume include s- naling mechanisms regulating the endothelium and smooth muscle cells,in?ammatory cells, mediators, airway surface liquid, and pharmacological therapy that focuses on how in?amed airways are altered. Written primarily for predoctoral and postdoctoral graduates in the basic medical sciences, the medical student and postdoctoral physician, graduates in the allied s- ences, nurses, pulmonologists, and physicians in critical care medicine, this book p- vides many of the fundamentals of contemporary pulmonology. It is divided into several parts devoted to the control of respiration, arterial chemoreceptors,muscles of ventilation, pulmonary physiology, and gas exchange in health, exercise, and disease. Special emphasis is placed on emphysema and its pathobiology, acute lung injury, asthma and inhaled toxicants. Because the ?eld is always evolving, each chapter includes recommended readings that lead the reader to sources of additional information, such as the review on remodeling of the blood gas barrier by West and Mathieu-Costello. 

 Anatomy and Ultrastructure of the Lung -- Biology of Mammalian Airway Epithelium -- Alveolar Surfactant -- Regulation of the Airway Caliber -- Receptors and Reflexes of the Respiratory Tract -- The Control of Respiration -- Arterial Chemoreceptors -- The Respiratory Muscles in Health and Disease -- Mechanics of Respiration -- The Physiology and Pathophysiology of Gas Exchange -- The Pulmonary Circulation in Health and Disease -- Regulation of Lung Water: Role of the Bronchial Circulation -- Airway Wall Liquid in Health and Disease -- Correlations Between the Pulmonary Circulation and Gas Exchange in Health and Disease -- Respiratory Regulation of Acid-Base Balance in Health and Disease -- Exercise and Breathing in Health and Disease -- High-Altitude Physiology and Pathophysiology -- Lung Immunology and Host Defense -- Acute Lung Injury -- Asthma -- Pathobiology of Emphysema -- Inhaled Noninfectious Toxicants and Their Effects on the Lung.