Metabolome Analyses: Strategies for Systems Biology

• Corporate Author: SpringerLink (Online service)
• Other Authors: Vaidyanathan, Seetharaman (Editor), Harrigan, George G. (Editor), Goodacre, Royston (Editor)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US, 2005.
• Subjects: Life sciences.; Analytical chemistry.; Internal medicine.; Biochemistry.; Bioinformatics.; Life Sciences.; Internal Medicine.; Analytical Chemistry.; Biochemistry, general.

Metabolome Analyses is intended as a follow-up to Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis (Kluwer, 2003). That text offered guidelines to currently available technology, bioinformatics and databases. Evidence was presented showing metabolic profiling as a valu...

Table of Contents:

• Towards Integrative Functional Genomics Using Yeast as a Reference Model
• Metabolomics for the Assessment of Functional Diversity and Quality Traits in Plants
• Metabolomics: A New Approach Towards Identifying Biomarkers and Therapeutic Targets in CNS Disorders
• Comparative Metabolome Profiling Using Two Dimensional Thin Layer Chromatography (2DTLC)
• Capillary Electrophoresis and Its Application in Metabolome Analysis
• Metabolite Profiling with GC-MS and LC-MS
• The Application of Electrochemistry to Metabolic Profiling
• Differential Metabolic Profiling for Biomarker Discovery
• NMR-Based Metabonomics in Toxicology Research
• Methodological Issues and Experimental Design Considerations in Metabolic Profile-Based Classifications
• Modelling of Fungal Metabolism
• Detailed Kinetic Models Using Metabolomics Data Sets
• Metabolic Networks
• Metabolic Networks from a Systems Perspective
• Parallel Metabolite and Transcript Profiling
• Fluxome Profiling in Microbes
• Targeted Drug Design and Metabolic Pathway Flux
• Metabonomics in the Pharmaceutical Industry
• How Lipidomic Approaches Will Benefit the Pharmaceutical Industry
• Metabolites and Fungal Virulence.