Hypocretins Integrators of Physiological Functions /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Lecea, Luis de (Επιμελητής έκδοσης), Sutcliffe, J. Gregor (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Boston, MA : Springer US, 2005.
• Θέματα: Medicine.; Neurosciences.; Endocrinology.; Neurology.; Biomedicine.

The first report that rapid eye movements occur in sleep in humans was published in 1953. The research journey from this point to the realization that sleep consists of two entirely independent states of being (eventually labeled REM sleep and non-REM sleep) was convoluted, but by 1960 the fundament...

Πίνακας περιεχομένων:

• Discovery of the Hypocretins/Orexins and Their Receptors
• The Discovery of the Hypocretins
• Orexin and Orexin Receptors
• Animal Models in the Study of the Hypocretinergic System
• Rodent Models of Human Narcolepsy-cataplexy
• The Canine Model of Narcolepsy
• Detailed Anatomy of the Hypocretinergic System and Related Hypothalamic Circuits
• Anatomy of the Hypocretin System
• The Anatomy of Hypocretin Neurons
• Transmitter-Identified Neurons and Afferent Innervation of the Lateral Hypothalamic Area
• Physiological Consequences of Hypocretin Activation
• Physiological Characteristics of Hypocretin/Orexin Neurons
• The Ne System as a Target for Hypocretin Neurons
• Hypocretin/Orexin Actions on Mesopontine Cholinergic Systems Controling Behavioral State
• The Aminergic Systems and the Hypocretins
• Effects Of Hypocretin/Orexin on the Thalamocortical Activating System
• Pharmacology of the Hypocretins and Drug Design
• In Vivo Pharmacology of Orexin (Hypocretin) Receptors
• Intracellular Signal Pathways Utilized by the Hypocretin/Orexin Receptors
• The Hypocretins in Narcolepsy and Arousal
• The Hypocretins and Narcolepsy
• An Approach to Determining the Functions of Hypocretin (Orexin)
• Hypocretin in Neuropsychiatric Disorders
• Hypocretin/Orexin and Sleep
• Modulation of Cortical Activity and Sleep-Wake States by Hypocretin/Orexin
• The Hypocretins in Feeding and Energy Balance
• Regulation of Hypocretin by Metabolic Signals
• The Hypocretins in Addiction and Hyperarousal
• Hypocretin and Brain Reward Function
• Orexin/Hypocretin and Opioid Dependence
• Dopamine-Hypocretin/Orexin Interactions
• Hypocretin/Orexin in Stress and Arousal
• Role of Hypocretins on Peripheral Systems
• The Hypocretins/Orexins and the Hypothalamo-Pituitary-Adrenal Axis
• Orexins (Hypocretins) in the Gut
• Hypocretins in Endocrine Regulation
• The Hypocretins in Cardiovascular Regulation.