In vivo Models of HIV Disease and Control

• Corporate Author: SpringerLink (Online service)
• Other Authors: Friedman, Herman (Editor), Specter, Steven (Editor), Bendinelli, Mauro (Editor)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US, 2006.
• Series: Infectious Diseases and Pathogenesis,
• Subjects: Medicine.; Immunology.; Allergy.; Infectious diseases.; Microbiology.; Medicine & Public Health.; Infectious Diseases.; Allergology.

An AIDS vaccine is still elusive and HIV treatment continues to develop multidrug resistance at alarming rates. Because of the similarities between HIV and immune deficiency infections in a variety of animals, it is only natural that scientists use these animals as models to study pathogenesis, trea...

Table of Contents:

• Historical Perspective
• Animal Model Systems of HIV-Diseases
• Chemokines and Their Receptors and the Neuropathogenesis of HIV-1 Infection
• SCID Mice Transplanted With Human Cells as Small Animal Models in AIDS Research
• SIV as a Model for AIDS Pathogenesis Studies
• SIV Infection of Macaques as a Model for AIDS Drug Studies
• FIV as a Model for HIV: An Overview
• FIV as a Model for AIDS Pathogenesis Studies
• Drugs of Abuse, AIDS, and the FIV Model
• FIV as a Model for AIDS Vaccine Studies
• FIV as a Model for HIV Treatment
• Equine Infectious Anemia Virus as a Model for Lentiviral Pathogenesis
• Studies of the Structure of Caprine Arthritis-Encephalitis Virus Surface Envelope Glycoprotein
• Ethical Issues in the Use of Animal Models of Infection and Some Practical Refinements
• Future Perspectives.