The Evaluation of Surrogate Endpoints

• Corporate Author: SpringerLink (Online service)
• Other Authors: Burzykowski, Tomasz (Editor), Molenberghs, Geert (Editor), Buyse, Marc (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York, 2005.
• Series: Statistics for Biology and Health,
• Subjects: Statistics.; Statistics for Life Sciences, Medicine, Health Sciences.

Both humanitarian and commercial considerations have spurred intensive search for methods to reduce the time and cost required to develop new therapies. The identification and use of surrogate endpoints, i.e., measures that can replace or supplement other endpoints in evaluations of experimental tre...