Pharmacokinetic-Pharmacodynamic Modeling and Simulation

• Main Author: Bonate, Peter L. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US, 2006.
• Subjects: Medicine.; Pharmacology.; Biomedicine.; Pharmacology/Toxicology.

This book presents both the art and science behind pharmacokinetic-pharmacodynamic modeling. Using a building-block approach, the author starts from linear and nonlinear models at the individual level and proceeds to develop more complex linear and nonlinear mixed effects models at the population le...

Table of Contents:

• The Art of Modeling
• Linear Models and Regression
• Nonlinear Models and Regression
• Variance Models, Weighting, and Transformations
• Case Studies in Linear and Nonlinear Modeling
• Linear Mixed Effects Models
• Nonlinear Mixed Effects Models: Theory
• Nonlinear Mixed Effects Models: Practical Issues
• Nonlinear Mixed Effects Models: Case Studies.