DNA Methylation and Cancer Therapy
NA methylation has bewildered molecular biologists since Hotchkiss discovered it almost six decades ago (Hotchkiss RDJ. Biol Cem 1948; 175:315-332). The fact that the chemical structure of our D genome consists of two components that are covalently bound, the genetic information that is replicated b...
| Κύριος συγγραφέας: | |
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| Συγγραφή απο Οργανισμό/Αρχή: | |
| Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Boston, MA :
Springer US,
2005.
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| Σειρά: | Medical Intelligence Unit
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| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- DNA Methylation
- Epigenetic Mechanisms of Gene Regulation
- DNA Hypo- vs. Hypermethylation in Cancer
- DNA Methylation in Urological Cancers
- DNA Methylation in Colorectal Cancer
- CpG Island Hypermethylation of Tumor Suppressor Genes in Human Cancer
- The Loss of Methyl Groups in DNA of Tumor Cells and Tissues
- Identifying Clinicopathological Association of DNA Hypermethylation in Cancers Using CpG Island Microarrays
- Methylation Analysis in Cancer
- Regulation of DNA Methyltransferases in Cancer
- Inhibition of Poly(ADP-Ribosyl)ation Allows DNA Hypermethylation
- The Role of Active Demethylation in Cancer and Its Therapeutic Potential
- Purine Analogues and Their Role in Methylation and Cancer Chemotherapy
- DNA Methyltransferase Inhibitors
- Preclinical and Clinical Studies on 5-Aza-2?-Deoxycytidine, a Potent Inhibitor of DNA Methylation, in Cancer Therapy
- Anticancer Gene Therapy by in Vivo DNA Electrotransfer of MBD2 Antisense
- Epilogue.
