Gene Therapy of Autoimmune Diseases

• Main Author: Prud’homme, Gérald J. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US, 2005.
• Series: Medical Intelligence Unit
• Subjects: Medicine.; Human genetics.; Immunology.; Biomedicine.; Human Genetics.

Autoimmune diseases are diverse and responsible for considerable morbidity. Their etiology remains largely unknown, and current therapy with anti-inflammatory drugs is prone to adverse effects, and rarely curative. New therapies with anti-cytokine antibodies or receptors are promising, but require f...

Table of Contents:

• Gene Therapy Approaches for Autoimmune Diseases of the Central Nervous System and Other Tissues
• Gene Therapeutics in Autoimmune Diabetes
• Immunogene Therapy with Nonviral Vectors
• Targeting Antigen-Specific T Cells for Gene Therapy of Autoimmune Disease
• Therapeutic Gene Transfer for Rheumatoid Arthritis
• Gene Therapy-Based Approach for Immune Tolerance Induction Using Recombinant Immunoglobulin Carriers
• DNA Vaccination against Autoimmune Diseases.