Computational Genome Analysis An Introduction /

• Main Authors: Deonier, Richard C. (Author), Waterman, Michael S. (Author), Tavaré, Simon (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York, 2005.
• Subjects: Computer science.; Mathematical statistics.; Bioinformatics.; Biomathematics.; Statistics.; Computer Science.; Computational Biology/Bioinformatics.; Genetics and Population Dynamics.; Statistics for Life Sciences, Medicine, Health Sciences.; Probability and Statistics in Computer Science.

Computational Genome Analysis: An Introduction presents the foundations of key problems in computational molecular biology and bioinformatics. It focuses on computational and statistical principles applied to genomes, and introduces the mathematics and statistics that are crucial for understanding t...

Table of Contents:

• Biology in a Nutshell
• Words
• Word Distributions and Occurrences
• Physical Mapping of DNA
• Genome Rearrangements
• Sequence Alignment
• Rapid Alignment Methods: FASTA and BLAST
• DNA Sequence Assembly
• Signals in DNA
• Similarity, Distance, and Clustering
• Measuring Expression of Genome Information
• Inferring the Past: Phylogenetic Trees
• Genetic Variation in Populations
• Comparative Genomics.