Lysosomes

• Main Author: Saftig, Paul (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US, 2005.
• Series: Medical Intelligence Unit
• Subjects: Life sciences.; Human genetics.; Neurosciences.; Biochemistry.; Cell biology.; Life Sciences.; Cell Biology.; Biochemistry, general.; Human Genetics.

Lysosomes are membrane-surrounded organelles which are present in all animal cells. The importance of this organelle is underlined by an increasing number of human diseases, which are associated with an impaired function of the lysosomal compartment. This book summarizes the current state-of-the art...

Table of Contents:

• History and Morphology of the Lysosome
• Transport of Lysosomal Enzymes
• Adaptor Proteins in Lysosomal Biogenesis
• Lysosomal Membrane Proteins
• Lysosomal Proteases
• Lysosomal Storage Disorders
• Lysosomal Transporters and Associated Diseases
• Neuronal Ceroid-Lipofuscinoses
• Cholesterol Transport in Lysosomes
• Therapy of Lysosomal Storage Diseases
• Lysosomal Proteome and Transcriptome
• External Lysosomes
• Membrane Resealing Mediated by Lysosomal Exocytosis
• Macroautophagy in Mammalian Cells
• Chaperone-Mediated Autophagy.