CD137 Pathway: Immunology and Diseases

• Corporate Author: SpringerLink (Online service)
• Other Authors: Chen, Lieping (Editor)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US, 2007.
• Subjects: Medicine.; Immunology.; Molecular biology.; Microbiology.; Biomedicine.; Molecular Medicine.

This comprehensive volume, written by experts in the field, covers nearly all aspects of ongoing research related to the CD137 pathway. Recent research has shown that the manipulation of CD137 pathway molecules is very promising in the treatment of cancer, viral infection, transplantation rejection...

Table of Contents:

• Genes, Transcripts and Proteins of CD137 Receptor and Ligand
• CD137 Signal Transduction
• Significance of Reverse Signal Transduction for the Biology of the CD137 Receptor/Ligand System
• CD137 Signal in the Regulation of Innate Immunity
• Regulation of T Cell-Dependent Humoral Immunity Through CD137 (4-1BB) Mediated Signals
• CD137 in the Regulation of T Cell Response to Antigen
• Autoimmune Diseases
• CD137/CD137 Ligand in Tumor and Viral Immunotherapy.