NF-κB/Rel Transcription Factor Family

• Corporate Author: SpringerLink (Online service)
• Other Authors: Liou, Hsiou-Chi (Editor)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US, 2006.
• Series: Molecular Biology Intelligence Unit
• Subjects: Life sciences.; Immunology.; Pharmacology.; Cell biology.; Microbiology.; Life Sciences.; Cell Biology.; Pharmacology/Toxicology.

Since its first discovery in the early 90’s, the NF-kB/Rel transcription factor family has drawn the attention of experimental biologists, medical profession, and biotech/pharmaceutical industries for its broad and diverse roles in all aspects of human biology and disease. NF-kB/Rel Transcription Fa...

Table of Contents:

• Structural Analysis of NF-?B and I?B Proteins
• NF-?B Signal Transduction by IKK Complexes
• Receptors and Adaptors for NF-?B Signaling
• Cellular Dynamics of NF-?B Associated Proteins
• NF-?B in Lymphopoiesis
• NF-?B and Immune Cell Effector Functions
• Roles of NF-?B in Autoimmunity
• The Central Role of NF-?B in the Regulation of Immunity to Infection
• Molecular Basis of Oncogenesis by NF-?B
• NF-?B in Human Cancers
• NF-?B in Neurons
• Inhibitors of NF-?B Activity.