Principles of Protein X-Ray Crystallography

• Κύριος συγγραφέας: Drenth, Jan (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York, 2007.
• Θέματα: Life sciences.; Analytical chemistry.; Biochemistry.; Biophysics.; Biological physics.; Environmental law.; Environmental policy.; Life Sciences.; Biochemistry, general.; Analytical Chemistry.; Biophysics and Biological Physics.; Environmental Law/Policy/Ecojustice.

X-ray crystallography has long been a vital method for studying the structure of proteins and other macromolecules. As the importance of proteins continues to grow, in fields from biochemistry and biophysics to pharmaceutical development and biotechnology, many researchers have found that a knowledg...

Πίνακας περιεχομένων:

• Crystallizing a Protein
• X-ray Sources and Detectors
• Crystals
• Theory of X-ray Diffraction by a Crystal
• Average Reflection Intensity and Distribution of Structure Factor Data
• Special Forms of the Structure Factor
• The Solution of the Phase Problem by the Isomorphous Replacement Method
• Phase Improvement
• Anomalous Scattering in the Determination of the Protein Phase Angles and the Absolute Configuration
• Molecular Replacement
• Direct Methods
• Laue Diffraction
• Refinement of the Model Structure
• The Combination of Phase Information
• Checking for Gross Errors and Estimating the Accuracy of the Structural Model
• Practical Protein Crystallization.