Power Laws, Scale-Free Networks and Genome Biology

• Main Authors: Koonin, Eugene V. (Author), Wolf, Yuri I. (Author), Karev, Georgy P. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US, 2006.
• Series: Molecular Biology Intelligence Unit
• Subjects: Physics.; Biochemistry.; Proteomics.; Bioinformatics.; Microbial genetics.; Microbial genomics.; Biophysics.; Biological physics.; Biophysics and Biological Physics.; Biochemistry, general.; Microbial Genetics and Genomics.; Physics, general.

Power Laws, Scale-free Networks and Genome Biology deals with crucial aspects of the theoretical foundations of systems biology, namely power law distributions and scale-free networks which have emerged as the hallmarks of biological organization in the post-genomic era. The chapters in the book not...

Table of Contents:

• Power Laws in Biological Networks
• Graphical Analysis of Biocomplex Networks and Transport Phenomena
• Large-Scale Topological Properties of Molecular Networks
• The Connectivity of Large Genetic Networks
• The Drosophila Protein Interaction Network May Be neither Power-Law nor Scale-Free
• Birth and Death Models of Genome Evolution
• Scale-Free Evolution
• Gene Regulatory Networks
• Power Law Correlations in DNA Sequences
• Analytical Evolutionary Model for Protein Fold Occurrence in Genomes, Accounting for the Effects of Gene Duplication, Deletion, Acquisition and Selective Pressure
• The Protein Universes
• The Role of Computation in Complex Regulatory Networks
• Neutrality and Selection in the Evolution of Gene Families
• Scaling Laws in the Functional Content of Genomes.