Fas Signaling

• Main Author: Wajant, Harald (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US, 2006.
• Series: Medical Intelligence Unit
• Subjects: Medicine.; Immunology.; Molecular biology.; Oncology.; Biomedicine.; Molecular Medicine.

Fas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alte...

Table of Contents:

• FasL and Fas
• FasL-Independent Activation of Fas
• Role of Ceramide in CD95 Signaling
• Regulation of Fas Signaling by FLIP Proteins
• Fas-Induced Necrosis
• Fas—More Than an Apoptosis Inducer
• Retrograde Fas Ligand Signaling
• FasL and Fas in Liver Homeostasis and Hepatic Injuries
• Fas-Activation, Development and Homeostasis of T Cells
• The FasL-Fas System in Disease and Therapy
• Tools for Activation and Neutralization of Fas Signaling.