Poly(ADP-Ribosyl)ation

• Κύριος συγγραφέας: Bürkle, Alexander (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Boston, MA : Springer US, 2006.
• Σειρά: Molecular Biology Intelligence Unit
• Θέματα: Medicine.; Human genetics.; Medical microbiology.; Biochemistry.; Cell biology.; Biomedicine.; Medical Microbiology.; Human Genetics.; Biochemistry, general.; Cell Biology.

Poly(ADP-Ribosyl)ation comprises 19 chapters written by leading international experts in the field and is richly illustrated. Extensive bibliography is given in each chapter.

Πίνακας περιεχομένων:

• Enzymes in Poly(ADP-Ribose) Metabolism
• PARP-2: Structure-Function Relationship
• Targeting the Poly (ADP-Ribose) Glycohydrolase (PARG) Gene in Mammals
• DNA Damage Signaling through Poly(ADP-Ribose)
• Roles of Poly(ADP-Ribose) Metabolism in the Regulation of Centrosome Duplication and in the Maintenance of Neuronal Integrity
• Functional Interactions of PARP-1 with p53
• Dynamic Interaction between PARP-1, PCNA and p21waf1/cip1
• PARP-1 as Novel Coactivator of NF-?B in Inflammatory Disorders
• PARP and Epigenetic Regulation
• PARP and the Release of Apoptosis-Inducing Factor from Mitochondria
• Genome Degradation by DNAS1L3 Endonuclease
• NAD: Metabolism and Regulatory Functions
• PARP-1 and the Shape of Cell Death
• Poly(ADP-Ribose) Polymerase (PARP) and Excitotoxicity
• Poly(ADP-Ribose) Polymerase and Ischemia-Reperfusion Injury
• Role of Poly(ADP-Ribose) Polymerase Activation in the Pathogenesis of Inflammation and Circulatory Shock
• Role of Poly-ADP-Ribosylation in Cancer Development
• PARP Inhibitors and Cancer Therapy
• Poly(ADP-Ribosyl)ation and Aging.