Shh and Gli Signalling and Development

he hedgehog signalling pathway is highly conserved and seen in organisms ranging from Drosophila to humans. This pathway is Tcritical in determining cell fate decisions in a variety of different cell types. There are several vertebrate analogues of the Drosophila hedgehog protein of which the most w...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Fisher, Carolyn E. (Συγγραφέας), Howie, Sarah E. M. (Συγγραφέας)
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: New York, NY : Springer New York, 2007.
Σειρά:Molecular Biology Intelligence Unit
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
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100 1 |a Fisher, Carolyn E.  |e author. 
245 1 0 |a Shh and Gli Signalling and Development  |h [electronic resource] /  |c by Carolyn E. Fisher, Sarah E. M. Howie. 
264 1 |a New York, NY :  |b Springer New York,  |c 2007. 
300 |a XI, 158 p. 40 illus., 4 illus. in color.  |b online resource. 
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490 1 |a Molecular Biology Intelligence Unit 
505 0 |a Sonic Hedgehog Signalling in Dorsal Midline and Neural Development -- Role of Hedgehog and Gli Signalling in Telencephalic Development -- Role of Shh and Gli Signalling in Oligodendroglial Development -- The Role of Sonic Hedgehog Signalling in Craniofacial Development -- Multiple Roles for Hedgehog Signalling in Zebrafish Eye Development -- Sonic Hedgehog Signalling during Tooth Morphogenesis -- Limb Pattern Formation -- Sonic Hedgehog Signalling in the Developing and Regenerating Fins of Zebrafish -- Hedgehog Signalling in T Lymphocyte Development -- Hedgehog Signalling in Prostate Morphogenesis -- Sonic Hedgehog Signalling in Visceral Organ Development -- Shh/Gli Signalling during Murine Lung Development -- New Perspectives in Shh Signalling?. 
520 |a he hedgehog signalling pathway is highly conserved and seen in organisms ranging from Drosophila to humans. This pathway is Tcritical in determining cell fate decisions in a variety of different cell types. There are several vertebrate analogues of the Drosophila hedgehog protein of which the most widely studied is Sonic hedgehog (Shh). Shh signalling classically involves the Gli family of zinc-fmger transcription factors. The Shh signalling pathway is well characterised in the develop­ ment of a number of vertebrate organ systems. It could indeed be argued that the Shh and Gli signalling may well be involved at some stage in the development of all the major organ systems in vertebrates. This volume rep­ resents a concerted drive to bring together *state of the art' reviews by lead­ ing experts in the field of Shh and Gli signalling in development from all over the world. The chapters span vertebrate organisms from zebrafish to humans and cover development of the multiple organ systems in which the Shh signalling pathway is crucial for normal development. There are chap­ ters on the development of the central nervous system, skeletal struc­ tures, visceral organs, prostate, lung, immune system and the structures of the human face. The authors themselves span three major continents and multiple nationalities which admirably illustrates the worldwide nature of the science. 
650 0 |a Life sciences. 
650 0 |a Human physiology. 
650 0 |a Cell biology. 
650 0 |a Developmental biology. 
650 1 4 |a Life Sciences. 
650 2 4 |a Developmental Biology. 
650 2 4 |a Cell Biology. 
650 2 4 |a Human Physiology. 
700 1 |a Howie, Sarah E. M.  |e author. 
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776 0 8 |i Printed edition:  |z 9780387399560 
830 0 |a Molecular Biology Intelligence Unit 
856 4 0 |u http://dx.doi.org/10.1007/978-0-387-39957-7  |z Full Text via HEAL-Link 
912 |a ZDB-2-SBL 
950 |a Biomedical and Life Sciences (Springer-11642)