Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Csermely, Peter (Επιμελητής έκδοσης), Vígh, László (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York, 2007.
• Σειρά: Advances in Experimental Medicine and Biology, 594
• Θέματα: Life sciences.; Immunology.; Biochemistry.; Cell biology.; Biophysics.; Biological physics.; Life Sciences.; Biochemistry, general.; Cell Biology.; Biophysics and Biological Physics.

We are extremely happy to present the reader this book containing a summary of a well-known research field, the phenomenon of cellular stress defense from two new angles: networks and membranes. The volume starts with an introduction to the concept of molecular chaperones in their original sense: R....

Πίνακας περιεχομένων:

• Protein Misassembly
• The Cellular “Networking” of Mammalian Hsp27 and Its Functions in the Control of Protein Folding, Redox State and Apoptosis
• Molecular Interaction Network of the Hsp90 Chaperone System
• Organization of the Functions and Components of the Endoplasmic Reticulum
• Molecular Crime and Cellular Punishment
• Chaperones as Parts of Cellular Networks
• Chaperones as Parts of Organelle Networks
• Heat Shock Factor 1 as a Coordinator of Stress and Developmental Pathways
• Chaperone Regulation of the Heat Shock Protein Response
• Mechanisms of Activation and Regulation of the Heat Shock-Sensitive Signaling Pathways
• Membrane-Regulated Stress Response
• Beyond the Lipid Hypothesis
• Trehalose As a “Chemical Chaperone”
• Chaperones As Part of Immune Networks
• The Stress of Misfolded Proteins
• Hsp90 and Developmental Networks.