Microarray Technology and Cancer Gene Profiling

• Corporate Author: SpringerLink (Online service)
• Other Authors: Mocellin, Simone (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York, 2007.
• Series: Advances in Experimental Medicine and Biology, 593
• Subjects: Medicine.; Cancer research.; Oncology.; Medicine & Public Health.; Cancer Research.

Cancer is a heterogeneous disease in most respects, including its cellularity, different genetic alterations and diverse clinical behaviors. Traditional molecular analyses are reductionist, assessing only one or a few genes at a time, thus working with a biologic model too specific and limited to co...

Table of Contents:

• Microarray Technology
• Manufacturing of Microarrays
• Technological Platforms for Microarray Gene Expression Profiling
• Principles of Gene Microarray Data Analysis
• Gaining Weights ... and Feeling Good about It!
• Complementary Techniques
• Complementary Techniques
• Complementary Techniques
• Applications in the Oncology Field
• Microarrays for Cancer Diagnosis and Classification
• Gene Profiling for the Prediction of Tumor Response to Treatment
• Identification of Molecular Determinants of Tumor Sensitivity and Resistance to Anticancer Drugs
• SNP and Mutation Analysis
• Cancer Development and Progression
• Gene Expression Profiling in Malignant Lymphomas
• Tumor Immunology.