Mechanisms of Lymphocyte Activation and Immune Regulation XI B Cell Biology /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Gupta, Sudhir (Επιμελητής έκδοσης), Alt, Frederick (Επιμελητής έκδοσης), Cooper, Max (Επιμελητής έκδοσης), Melchers, Fritz (Επιμελητής έκδοσης), Rajewsky, Klaus (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Boston, MA : Springer US, 2007.
• Σειρά: Advances in Experimental Medicine and Biology, 596
• Θέματα: Medicine.; Immunology.; Pharmacology.; Virology.; Infectious diseases.; Microbiology.; Biomedicine.; Infectious Diseases.; Pharmacology/Toxicology.

In recent years, major developments have been made in understanding various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires. These include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. A role...

Πίνακας περιεχομένων:

• Regulation and Function of the E2A Proteins in B Cell Development
• Multiple Roles for Blimp-1 in B and T Lymphocytes
• Memory B Cell Evolution: B Cell Biology
• BCR-linked Factors in Developmental Fate Decisions
• Gene Regulatory Networks that Orchestrate the Development of B Lymphocyte Precursors
• Rules for the Rearrangement Events at the L Chain Gene Loci of the Mouse
• Regulation of AID Function In Vivo
• Targeting of AID to Immunoglobulin Genes
• Targeting AID to the Ig Genes
• DNA Replication to Aid Somatic Hypermutation
• Regulation of Activation Induced Deaminase via Phosphorylation
• Modulation of MHC Class II Signal Transduction by CD19
• Role of NFUP?B Signaling in Normal and Malignant B Cell Development
• Fc Receptor–like Proteins (FCRL): Immunomodulators of B Cell Function
• Tolerance Mechanisms in the Late Phase of the Antibody Response
• Role of RS/?DE in B Cell Receptor Editing
• The Regulation of Receptor Editing
• B Cell Hyporesponsiveness and Autoimmunity: A New Paradigm.