Statistical Genetics of Quantitative Traits Linkage, Maps, and QTL /

• Main Authors: Wu, Rongling (Author), Casella, George (Author), Ma, Chang-Xing (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York, 2007.
• Series: Statistics for Biology and Health,
• Subjects: Life sciences.; Bioinformatics.; Biochemistry.; Plant genetics.; Animal genetics.; Biomathematics.; Statistics.; Life Sciences.; Biochemistry, general.; Animal Genetics and Genomics.; Plant Genetics & Genomics.; Computational Biology/Bioinformatics.; Statistics for Life Sciences, Medicine, Health Sciences.; Genetics and Population Dynamics.

The book introduces the basic concepts and methods that are useful in the statistical analysis and modeling of DNA-based marker and phenotypic data that arise in agriculture, forrestry, experimental biology, and other fields. It concentrates on the linkage analysis of markers, map construction and q...

Table of Contents:

• Basic Genetics
• Basic Statistics
• Linkage Analysis and Map Construction
• A General Model for Linkage Analysis in Controlled Crosses
• Linkage Analysis with Recombinant Inbred Lines
• Linkage Analysis for Distorted and Misclassified Markers
• Special Considerations in Linkage Analysis
• Marker Analysis of Phenotypes
• The Structure of QTL Mapping
• Interval Mapping with Regression Analysis
• Interval Mapping by Maximum Likelihood Approach
• Threshold and Precision Analysis
• Composite QTL Mapping
• QTL Mapping in Outbred Pedigrees.