Biological Membrane Ion Channels Dynamics, Structure, and Applications /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Chung, Shin-Ho (Editor), Andersen, Olaf S. (Editor), Krishnamurthy, Vikram (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York, 2007.
• Series: Biological And Medical Physics Biomedical Engineering,
• Subjects: Physics.; Neurosciences.; Biotechnology.; Biochemistry.; Neurobiology.; Biophysics.; Biological physics.; Biomedical engineering.; Biophysics and Biological Physics.; Biomedical Engineering.; Animal Biochemistry.

Ion channels are biological nanotubes that are formed by membrane proteins. Because ion channels regulate all electrical activities in living cells, understanding their mechanisms at a molecular level is a fundamental problem in biology. This book deals with recent breakthroughs in ion-channel resea...

Table of Contents:

• Ion Channels, from Fantasy to Fact in Fifty Years1
• Specific Channel Types
• Gramicidin Channels: Versatile Tools
• Voltage-Gated Ion Channels
• Voltage-Gated Potassium Channels
• BKCa-Channel Structure and Function
• Voltage-Gated Sodium Channels
• Calcium Channels
• Chloride Transporting CLC Proteins1
• Ligand-Gated Ion Channels: Permeation and Activation1
• Mechanosensitive Channels
• TRP Channels
• Ion Channels in Epithelial Cells
• Theoretical Approaches
• Poisson–Nernst–Planck Theory of Ion Permeation Through Biological Channels
• A Mesoscopic–Microscopic Perspective on Ion Channel Permeation Energetics: The Semi-Microscopic Approach1
• Brownian Dynamics: Simulation for Ion Channel Permeation1
• Molecular Dynamics Simulation Approaches to K Channels
• Emerging Technologies
• Patch-Clamp Technologies for Ion Channel Research
• Gated Ion Channel-Based Biosensor Device
• Signal Processing Based on Hidden Markov Models for Extracting Small Channel Currents.