Tumor-Induced Immune Suppression Mechanisms and Therapeutic Reversal /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Gabrilovich, Dmitry I. (Επιμελητής έκδοσης), Hurwitz, Arthur A. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York, 2008.
• Θέματα: Medicine.; Cancer research.; Human genetics.; Immunology.; Medical microbiology.; Cell biology.; Developmental biology.; Biomedicine.; Cancer Research.; Medical Microbiology.; Cell Biology.; Human Genetics.; Developmental Biology.

Tumor Induced Immune Suppression: Mechanisms and Therapeutic Reversal focuses on the critical question of tumor biology: "Why can tumors escape immune system control?" It also addresses one of the most important problems within the field of clinical oncology: the lack of efficient cancer v...

Πίνακας περιεχομένων:

• Immune-Suppressive Mechanisms and Cancer: Understanding the Implications, Paradoxes, and Burning Questions
• Mechanisms of Tumor-Associated T-Cell Tolerance
• Contribution of B7-H1/PD-1 Co-inhibitory Pathway to T-Cell Dysfunction in Cancer
• Regulatory T Cells in Cancer
• Cancer-Induced Signaling Defects in Antitumor T Cells
• Immunobiology of Dendritic Cells in Cancer
• Macrophages and Tumor Development
• Myeloid-Derived Suppressor Cells in Cancer
• Signaling Pathways in Antigen-Presenting Cells Involved in the Induction of Antigen-Specific T-Cell Tolerance
• Arginine Availability Regulates T-Cell Function in Cancer
• Protein–Glycan Interactions in the Regulation of Immune Cell Function in Cancer: Lessons from the Study of Galectins-1 and -3
• Role of Reactive Oxygen Species in T-Cell Defects in Cancer
• Tumor Stroma and the Antitumor Immune Response.