Modulation of Protein Stability in Cancer Therapy

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Rubin, Eric (Επιμελητής έκδοσης), Sakamoto, Kathleen (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer US, 2009.
• Θέματα: Medicine.; Cancer research.; Human genetics.; Immunology.; Medical microbiology.; Biochemistry.; Biomedicine.; Cancer Research.; Medical Microbiology.; Human Genetics.; Biochemistry, general.

This book contains chapters written by experts in the field of the ubiquitin proteasome system and cancer. The authors have summarized current information on ubiquitin ligases and proteasomes as potential targets for cancer therapy. Topics covered in the book include an overview of ubiquitin ligases...

Πίνακας περιεχομένων:

• Ubiquitin Ligases and Cancer
• The 26S Proteasome as a Therapeutic Target in Cancer: Beyond Protease Inhibitors?
• Targeting HAUSP: Killing Two Birds with One Stone
• Modulation of Protein Stability: Targeting the VHL Pathway
• Interrelationship of the Fanconi Anemia/BRCA Pathway
• Targeting the Sumoylation Pathway
• Proteasome Inhibitors
• Targeting Deubiquitinating Enzymes
• Proteolysis Targeting Chimeric Molecules.