Acute Myelogenous Leukemia Genetics, Biology and Therapy /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Nagarajan, Lalitha (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York, 2010.
• Έκδοση: 1.
• Σειρά: Cancer Treatment and Research, 145
• Θέματα: Medicine.; Hematology.; Oncology.; System theory.; Medicine & Public Health.; Systems Theory, Control.

Acute myelogenous leukemia (AML), is the most common form of leukemia in adults. AML is a deadly form of malignancy, the prognosis for which has not improved in the last two decades. More importantly, it is a malignancy that is seen in older adults, therefore the number of cases is likely to rise as...

Πίνακας περιεχομένων:

• The Leukemia Stem Cell
• Epigenetic Mechanisms in AML – A Target for Therapy
• Chromosomal Translocations in AML: Detection and Prognostic Significance
• Chromosomal Deletions in AML
• Genes Predictive of Outcome and Novel Molecular Classification Schemes in Adult Acute Myeloid Leukemia
• Receptor Tyrosine Kinase Alterations in AML – Biology and Therapy
• Lineage-Specific Transcription Factor Aberrations in AML
• Proleukemic RUNX1 and CBF? Mutations in the Pathogenesis of Acute Leukemia
• Acute Myeloid Leukemia with Mutated Nucleophosmin (NPM1): Molecular, Pathological, and Clinical Features
• MicroRNAs: New Players in AML Pathogenesis
• Murine Models of Human Acute Myeloid Leukemia
• Apoptosis in Leukemias: Regulation and Therapeutic Targeting
• Acute Promyelocytic Leukemia: A Paradigm for Differentiation Therapy
• Immunotherapy of AML
• Therapy of Acute Myelogenous Leukemia in Adults.