TNF Receptor Associated Factors (TRAFs)
It has been established that TNF receptor associated factors (TRAFs) are critical signaling mediators for not only the TNF receptor superfamily, but also the interleukin-1 receptor/Toll-like receptor superfamily and the T-cell receptors. They play important roles in mammalian biology including embry...
Συγγραφή απο Οργανισμό/Αρχή: | |
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Άλλοι συγγραφείς: | |
Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
Γλώσσα: | English |
Έκδοση: |
New York, NY :
Springer New York,
2007.
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Σειρά: | Advances in Experimental Medicine and Biology,
597 |
Θέματα: | |
Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Phylogeny of the TRAF/MATH Domain
- TRAF1 and Its Biological Functions
- Physiological Roles and Mechanisms of Signaling by TRAF2 and TRAF5
- TRAF3 and Its Biological Function
- TRAF4, the Unique Family Member
- Characteristics and Biological Functions of TRAF6
- Ubiquitination and TRAF signaling
- Structural Revelations of TRAF2 Function in TNF Receptor Signaling Pathway
- Protein-Protein Interactions in TRAF3
- Molecular Basis for the Unique Specificity of TRAF6
- TRAF Proteins in CD40 Signaling
- TRAFs in RANK Signaling
- The LT?R Signaling Pathway
- LMP1 TRAFficking Activates Growth and Survival pathways
- Targeting TRAFs for Therapeutic Intervention.