Cortical Deficits In Schizophrenia From Genes to Function /

• Corporate Author: SpringerLink (Online service)
• Other Authors: O'Donnell, Patricio (Editor)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US, 2008.
• Subjects: Medicine.; Human genetics.; Neurosciences.; Neurology.; Psychiatry.; Neuropsychology.; Cognitive psychology.; Biomedicine.; Human Genetics.; Cognitive Psychology.

The genetics of schizophrenia have taken the driver seat in the research related to this disorder in recent years. For a long time, it had been known that sharing genes with someone affected with schizophrenia conferred a 50% chance of acquiring the disease. Although this is fifty times the incidenc...

Table of Contents:

• Schizophrenia Genes: Searching for Common Features, Functions, and Mechanisms
• Towards a Molecular Classification of Illness: Effects of Schizophrenia Susceptibility Loci on Clinical Symptoms and Cognitive Function
• Homer: A Genetic Factor in Schizophrenia?
• Neuregulin-erbB Signaling and the Pathogenesis of Schizophrenia
• Nicotinic Cholinergic Cortical Dysfunction in Schizophrenia
• A Role for Glutamate Receptors, Transporters, and Interacting Proteins in Cortical Dysfunction in Schizophrenia
• Cortical Circuit Dysfunction in the NMDA Receptor Hypofunction Model for the Psychosis of Schizophrenia
• Alterations in Hippocampal Function in Schizophrenia: its Genetic Associations and Systems Implications
• Identifying Novel Target Genes in Psychotic Disorder Network Association Analyses
• Alterations in Cortical GABA Neurotransmission in Schizophrenia: Causes and Consequences
• Increased Cortical Excitability as a Critical Element in Schizophrenia Pathophysiology.