Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

• Corporate Author: SpringerLink (Online service)
• Other Authors: Vinks, Alexander A. (Editor), Derendorf, Hartmut (Editor), Mouton, Johan W. (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2014.
• Subjects: Medicine.; Immunology.; Medical microbiology.; Pharmacology.; Public health.; Infectious diseases.; Medicine & Public Health.; Infectious Diseases.; Pharmacology/Toxicology.; Medical Microbiology.; Public Health.

Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal...

Table of Contents:

• Foreword
• Section I: Basic Concepts and Principles
• Introduction to Pharmacodynamics and micrbiology
• In vitro and animal PK/PD model
• MIC and breakpoints
• Principles of applied PK/PD modeling
• Population Pk/PD modeling and its applications to antimicrobials
• Drug resistance and Drug-drug combinations
• Section II: Clinical
• Aminoglycosides
• Beta-lactam antibiotics including continuous infusion
• Macrolides
• Glycopeptides
• Quinolones
• Other.-      .