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03528nam a22004695i 4500 |
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978-0-387-77232-5 |
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100301s2008 xxu| s |||| 0|eng d |
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|a 9780387772325
|9 978-0-387-77232-5
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|a 10.1007/978-0-387-77232-5
|2 doi
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|a MED057000
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|a 612.8
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|a Structural And Functional Organization Of The Synapse
|h [electronic resource] /
|c edited by Johannes W. Hell, Michael D. Ehlers.
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|a Boston, MA :
|b Springer US,
|c 2008.
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|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
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|a online resource
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|a text file
|b PDF
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|a Diversity in Synapse Structure and Composition -- The Role of Glutamate Transporters in Synaptic Transmission -- Structure and Function of Vertebrate and Invertebrate Active Zones -- Neurotransmitter Release Machinery: Components of the Neuronal SNARE Complex and Their Function -- The Molecular Machinery for Synaptic Vesicle Endocytosis -- Initiation and Regulation of Synaptic Transmission by Presynaptic Calcium Channel Signaling Complexes -- Adhesion Molecules at the Synapse -- Dendritic Organelles for Postsynaptic Trafficking -- Structure and Mechanism of Action of AMPA and Kainate Receptors -- Cellular Biology of AMPA Receptor Trafficking and Synaptic Plasticity -- Structure and Function of the NMDA Receptor -- Molecular Properties and Cell Biology of the NMDA Receptor -- Surface Trafficking of Membrane Proteins at Excitatory and Inhibitory Synapses -- Scaffold Proteins in the Postsynaptic Density -- Ca2+ Signaling in Dendritic Spines -- Postsynaptic Targeting of Protein Kinases and Phosphatases -- Long-Term Potentiation -- Homeostatic Synaptic Plasticity -- Ubiquitin and Protein Degradation in Synapse Function -- Signaling from Synapse to Nucleus -- Molecular Organization of the Postsynaptic Membrane at Inhibitory Synapses -- Acid-Sensing Ion Channels (ASICs) and pH in Synapse Physiology -- Glia as Active Participants in the Development and Function of Synapses -- Plasticity of Dentate Granule Cell Mossy Fiber Synapses: A Putative Mechanism of Limbic Epileptogenesis -- Stroke – A Synaptic Perspective -- and Pathological Pain.
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|a Synapses play a central role in the brain by mediating signal transmission between neurons. This book provides a fundamental description of the synapse by leading experts in the field. Each individual synapse carries out its numerous functions in a tiny space, thereby requiring an exquisite molecular and functional arrangement. This book describes the molecular structure and cellular function of central synapses in the brain, providing a detailed view of the brain’s fundamental unit of information storage.
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|a Medicine.
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650 |
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|a Neurosciences.
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|a Neurology.
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|a Neurobiology.
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|a Biomedicine.
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|a Neurosciences.
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|a Neurobiology.
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|a Neurology.
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|a Hell, Johannes W.
|e editor.
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|a Ehlers, Michael D.
|e editor.
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710 |
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|a SpringerLink (Online service)
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|t Springer eBooks
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|i Printed edition:
|z 9780387772318
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|u http://dx.doi.org/10.1007/978-0-387-77232-5
|z Full Text via HEAL-Link
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|a ZDB-2-SBL
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|a Biomedical and Life Sciences (Springer-11642)
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