Structural And Functional Organization Of The Synapse

Synapses play a central role in the brain by mediating signal transmission between neurons. This book provides a fundamental description of the synapse by leading experts in the field. Each individual synapse carries out its numerous functions in a tiny space, thereby requiring an exquisite molecula...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Hell, Johannes W. (Επιμελητής έκδοσης), Ehlers, Michael D. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Boston, MA : Springer US, 2008.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
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505 0 |a Diversity in Synapse Structure and Composition -- The Role of Glutamate Transporters in Synaptic Transmission -- Structure and Function of Vertebrate and Invertebrate Active Zones -- Neurotransmitter Release Machinery: Components of the Neuronal SNARE Complex and Their Function -- The Molecular Machinery for Synaptic Vesicle Endocytosis -- Initiation and Regulation of Synaptic Transmission by Presynaptic Calcium Channel Signaling Complexes -- Adhesion Molecules at the Synapse -- Dendritic Organelles for Postsynaptic Trafficking -- Structure and Mechanism of Action of AMPA and Kainate Receptors -- Cellular Biology of AMPA Receptor Trafficking and Synaptic Plasticity -- Structure and Function of the NMDA Receptor -- Molecular Properties and Cell Biology of the NMDA Receptor -- Surface Trafficking of Membrane Proteins at Excitatory and Inhibitory Synapses -- Scaffold Proteins in the Postsynaptic Density -- Ca2+ Signaling in Dendritic Spines -- Postsynaptic Targeting of Protein Kinases and Phosphatases -- Long-Term Potentiation -- Homeostatic Synaptic Plasticity -- Ubiquitin and Protein Degradation in Synapse Function -- Signaling from Synapse to Nucleus -- Molecular Organization of the Postsynaptic Membrane at Inhibitory Synapses -- Acid-Sensing Ion Channels (ASICs) and pH in Synapse Physiology -- Glia as Active Participants in the Development and Function of Synapses -- Plasticity of Dentate Granule Cell Mossy Fiber Synapses: A Putative Mechanism of Limbic Epileptogenesis -- Stroke – A Synaptic Perspective -- and Pathological Pain. 
520 |a Synapses play a central role in the brain by mediating signal transmission between neurons. This book provides a fundamental description of the synapse by leading experts in the field. Each individual synapse carries out its numerous functions in a tiny space, thereby requiring an exquisite molecular and functional arrangement. This book describes the molecular structure and cellular function of central synapses in the brain, providing a detailed view of the brain’s fundamental unit of information storage. 
650 0 |a Medicine. 
650 0 |a Neurosciences. 
650 0 |a Neurology. 
650 0 |a Neurobiology. 
650 1 4 |a Biomedicine. 
650 2 4 |a Neurosciences. 
650 2 4 |a Neurobiology. 
650 2 4 |a Neurology. 
700 1 |a Hell, Johannes W.  |e editor. 
700 1 |a Ehlers, Michael D.  |e editor. 
710 2 |a SpringerLink (Online service) 
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776 0 8 |i Printed edition:  |z 9780387772318 
856 4 0 |u http://dx.doi.org/10.1007/978-0-387-77232-5  |z Full Text via HEAL-Link 
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950 |a Biomedical and Life Sciences (Springer-11642)