Bioconductor Case Studies

• Κύριοι συγγραφείς: Hahne, Florian (Συγγραφέας), Huber, Wolfgang (Συγγραφέας), Gentleman, Robert (Συγγραφέας), Falcon, Seth (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York, 2008.
• Έκδοση: 1.
• Σειρά: Use R!
• Θέματα: Life sciences.; Bioinformatics.; Biomathematics.; Statistics.; Life Sciences.; Life Sciences, general.; Statistics for Life Sciences, Medicine, Health Sciences.; Computational Biology/Bioinformatics.; Mathematical and Computational Biology.

Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Biocon...

Πίνακας περιεχομένων:

• The ALL Dataset
• R and Bioconductor Introduction
• Processing Affymetrix Expression Data
• Two Color Arrays
• Fold Changes, Log Ratios, Background Correction, Shrinkage Estimation, and Variance Stabilization
• Easy Differential Expression
• Differential Expression
• Annotation and Metadata
• Supervised Machine Learning
• Unsupervised Machine Learning
• Using Graphs for Interactome Data
• Graph Layout
• Gene Set Enrichment Analysis
• Hypergeometric Testing Used for Gene Set Enrichment Analysis
• Solutions to Exercises.