Drug Resistance in Cancer Cells

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Siddik, Zahid H. (Επιμελητής έκδοσης), Mehta, Kapil (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer US, 2009.
• Θέματα: Medicine.; Cancer research.; Pharmacology.; Biomedicine.; Cancer Research.; Pharmacology/Toxicology.

An estimated 1.5 million patients in the United States are diagnosed with cancer every year and over half-a-million individuals die of the disease. Since the vast majority of the deaths occur after medical intervention with anticancer therapy, both conventional chemotherapy and novel targeted therap...

Πίνακας περιεχομένων:

• Multidrug Resistance Mediated by MDR-ABC Transporters
• Metastasis and Drug Resistance
• The Role of Autophagy and Apoptosis in the Drug Resistance of Cancer
• Mechanisms of Resistance to Targeted Tyrosine Kinase Inhibitors
• Targeting Transglutaminase-2 to Overcome Chemoresistance in Cancer Cells
• Extracellular Matrix-Mediated Drug Resistance
• Oxidative Stress and Drug Resistance in Cancer
• Nuclear Factor-?B and Chemoresistance: How Intertwined Are They?
• Drug Resistance and the Tumor Suppressor p53: The Paradox of Wild-Type Genotype in Chemorefractory Cancers
• Resistance to Differentiation Therapy
• MicroRNAs and Drug Resistance
• Molecular Signatures of Drug Resistance
• Assessment of Drug Resistance in Anticancer Therapy by Nuclear Imaging
• Overcoming Drug Resistance by Phytochemicals.