Therapeutic Targets of the TNF Superfamily

Tumor necrosis factor (TNF) superfamily is a rapidly growing family of cytokines that interacts with a corresponding superfamily of receptors. Ligand-receptor interactions of this superfamily are involved in numerous biological processes ranging from hematopoiesis to pleiotropic cellular responses,...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Grewal, Iqbal S. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: New York, NY : Springer New York, 2009.
Σειρά:Advances in Experimental Medicine and Biology, 647
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Overview of TNF Superfamily: A Chest Full of Potential Therapeutic Targets
  • Therapeutic Interventions Targeting CD40L (CD154) and CD40: The Opportunities and Challenges
  • Targeting TNF for Treatment of Cancer and Autoimmunity
  • Targeting of BAFF and APRIL for Autoimmunity and Oncology
  • The Role of FasL and Fas in Health and Disease
  • OX40 (CD134) and OX40L
  • Targeting CD70 for Human Therapeutic Use
  • 4-1BB as a Therapeutic Target for Human Disease
  • RANK(L) as a Key Target for Controlling Bone Loss
  • Targeting the LIGHT-HVEM Pathway
  • GITR: A Modulator of Immune Response and Inflammation
  • Targeting CD30/CD30L in Oncology and Autoimmune and Inflammatory Diseases
  • Tumor Necrosis Factor Receptor Superfamily Member 21: TNFR-Related Death Receptor-6, DR6
  • TRAIL and Other TRAIL Receptor Agonists as Novel Cancer Therapeutics
  • Therapeutic Potential of VEGI/TL1A in Autoimmunity and Cancer.