Cellular Signaling in Health and Disease

• Main Author: Beckerman, Martin (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer US, 2009.
• Series: Biological and Medical Physics, Biomedical Engineering,
• Subjects: Physics.; Human physiology.; Molecular biology.; Biochemistry.; Cell biology.; Biophysics.; Biological physics.; Biomedical engineering.; Biophysics and Biological Physics.; Human Physiology.; Cell Biology.; Molecular Medicine.; Biomedical Engineering.; Biochemistry, general.

In today’s world, three great classes of non-infectious diseases – the metabolic syndromes (such as type 2 diabetes and atherosclerosis), the cancers, and the neurodegenerative disorders – have risen to the fore. These diseases, all associated with increasing age of an individual, have proven to be...

Table of Contents:

• Metabolic Syndromes
• Energy Balance
• Insulin Signaling and Type 2 Diabetes
• Metabolic Program Execution and Switching
• Cholesterol
• Atherosclerosis
• Chronic Inflammation
• Redox Signaling
• Cancer
• The Cell Cycle
• Cell Cycle Checkpoints and DNA Damage Repair
• Apoptosis and Senescence
• Epigenetics
• Tumor Growth
• Tumor Metabolism
• Metastasis
• Neurodegeneration
• Protein Folding, Misfolding, and Aggregation
• Alzheimer’s Disease
• Chaperones, Endoplasmic Reticulum Stress, and the Unfolded Protein Response
• Parkinson’s Disease
• Huntington’s Disease and Amyotrophic Lateral Sclerosis.